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Merck
CN

M-144

MDAI hydrochloride solution

100 μg/mL in acetonitrile: water (9:1) with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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经验公式(希尔记法):
C10H11NO2 · HCl
化学文摘社编号:
分子量:
213.66
NACRES:
NA.24
UNSPSC Code:
41116107
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InChI

1S/C10H11NO2.ClH/c11-8-1-6-3-9-10(13-5-12-9)4-7(6)2-8;/h3-4,8H,1-2,5,11H2;1H

InChI key

DEZYWEZDXRXACY-UHFFFAOYSA-N

SMILES string

Cl.NC1Cc2cc3OCOc3cc2C1

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule E (Switzerland); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet

concentration

100 μg/mL in acetonitrile: water (9:1) with 5% 1 M HCl (as free base)

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−70°C

General description

MDAI, or 5,6-Methylenedioxy-2-aminoindane, is a new stimulant and club/designer drug with significant cases of abuse reported in Asia, Europe and the US. Sold over the Internet as a “bath salt,” MDAI is a potential successor to mephedrone as the next legal high drug.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

55.4 °F - closed cup

flash_point_c

13 °C - closed cup

法规信息

监管及禁止进口产品
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Cathal T Gallagher et al.
Human psychopharmacology, 27(2), 106-112 (2012-03-06)
The fully synthetic 'legal high' 5,6-methylenedioxy-2-aminoindane (MDAI) is an analogue of 3,4-methylenedioxymethamphetamine. Although developed in the 1990s, it was not widely abused until 2010. However, mephedrone was banned in the UK in April 2010, and almost immediately, MDAI was widely
R Oberlender et al.
The Journal of pharmacology and experimental therapeutics, 255(3), 1098-1106 (1990-12-01)
The stimulus properties of 3,4-methylenedioxymethamphetamine (MDMA)-like compounds were studied in rats trained to discriminate saline from (+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine [(+)-MBDB] hydrochloride (7.18 mumol/kg; 1.75 mg/kg), the alpha-ethyl homolog of MDMA. In previous experiments with (+)-MBDB as a test drug, complete substitution was
M P Johnson et al.
Pharmacology, biochemistry, and behavior, 40(4), 915-922 (1991-12-01)
There is increasing evidence linking dopamine (DA) to the long-term serotonergic (5-HT) neurotoxic effects of certain substituted amphetamines such as 3,4-methylenedioxymethamphetamine (MDMA). The present study was undertaken to examine the importance of DA metabolism, uptake inhibition and release in the
Laurent Karila et al.
Drug testing and analysis, 3(9), 552-559 (2011-10-01)
Designer drugs belong to a group of legally or illegally produced substances that are structurally and pharmacologically very similar to illicit drugs. In the past, designer drugs were often used during all-night dance parties, but they are now consumed in
J E Sprague et al.
Biochemical pharmacology, 52(8), 1271-1277 (1996-10-25)
Studies were conducted to investigate the sensitivity of p-chloroamphetamine (PCA)-induced neurochemical changes to various pharmacological manipulations known to block the neurochemical effects of 3,4-methylenedioxymethamphetamine (MDMA). The monoamine oxidase-B (MAO-B) inhibitor L-deprenyl (2 mg/kg) given 4 hr before a nonneurotoxic dose

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