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安全信息

V-063

Supelco

泛酸-13C3,15N半钙盐标准液 半钙盐 溶液

100 μg/mL (90:10 Methanol:Water, (as free acid)), certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

经验公式（希尔记法）:
13C3C6H1615NO5 · 0.5Ca
CAS号:
356786-94-2
分子量:
242.24
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

100 μg/mL (90:10 Methanol:Water, (as free acid))

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

格式

single component solution

储存温度

−20°C

相关类别

一般描述

An internal standard suitable for quantitation of pantothenic acid levels and testing applications including clinical and diagnostic testing or quality control testing of vitamin supplements, fortified foods or pharmaceutical preparations. Pantothenic acid, also known as Vitamin B5, is an essential water-soluble B vitamin that is involved in the coenzyme A (CoA) synthesis.

应用


  • Enzyme inhibition studies: Stable isotope-labeled pantothenic acid is used in X-ray crystallography and NMR studies to understand the mechanism of homotropic inhibition in enzyme reactions, specifically pantothenate synthetase. Such studies are essential for drug design targeting metabolic pathways, enhancing the effectiveness of treatments involving vitamin B5 pathways (Chakrabarti et al., 2010).

  • NMR structural analysis: The labeled compound aids in the NMR structural elucidation of enzymes such as ketopantoate reductase, helping to determine its role in biological systems. This analysis is crucial for developing drugs that can manipulate these enzymatic pathways, impacting treatments for conditions requiring metabolic modulation (Headey et al., 2008).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

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