03-0134-00
SMC® Mouse IL-10 Discovery Immunoassay Kit
Used for ultrasensitive quantification of Mouse IL-10 in mouse serum and plasma.
别名:
mouse IL 10 immunoassay kit, mouse IL-10 Single Molecule Counting Kit, mouse IL-10 ultra-sensitive immunoassay, mouse Interleukin 10 immunoassay kit
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UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
Species reactivity:
mouse
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with Erenna instrument
General description
Interleukin-10 (IL-10) is a cytokine with both stimulatory and suppressive effects on the immune system. The protein originates from several cell lines, including Th2 cells, mast cells, macrophages, monocytes and B-cells. Its main functions are to impede inflammatory responses and to inhibit synthesis of other pro-inflammatory cytokines, such as IL-2, IL-3, GM-CSF, IFN-γ and TNF-α. Besides its anti-inflammatory capabilities, IL-10 also regulates the production of natural killer cells and lymphocytes. Due to its multiple roles, proper function of IL-10 is required to maintain a healthy immune system. Improper function of IL-10 can result in disease development, as over expression of IL-10 has been linked to lymphoma, whereas IL-10 deficiency has implications for Crohn′s disease.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Ultra-Sensitive Detection of Mouse IL-10: Enables quantification of low-abundance IL-10 in mouse serum, ideal for early immune response studies, inflammation models, and cytokine profiling.
- Specificity for Biologically Active IL-10: Provides accurate and selective measurement of IL-10, supporting mechanistic studies in immunoregulation and disease modeling.
- Ideal for Inflammation and Autoimmunity Research: IL-10 is a key anti-inflammatory cytokine involved in regulating Th1/Th2 balance, macrophage activity, and cytokine suppression. This kit supports disease modeling in Crohn’s, colitis, and lymphoma, where IL-10 dysregulation is implicated.
Packaging
96 well assay
Analysis Note
- Standard Curve Range: 1500-1,500,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Recovery: 80-120%
Legal Information
SMC is a registered trademark of Singulex
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1
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