产品名称
SMC® Human IL-13 High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human IL-13 in human serum and plasma
technique(s)
single molecule counting: suitable
product line
SMC®
usage
in. sufficient for 96 wells
species reactivity
human
manufacturer/tradename
SMC®
input
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
Legal Information
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
Analysis Note
- Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument
- Standard Curve Range: 20-100,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 95% Plasma: 100%
- Recovery: Serum: 88% Plasma: 89%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & Immunology Inflammatory Disease Immune Response Autoimmune Disease
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Biochem/physiol Actions
Although IL-13 was detectable in guinea pig, non-human primate, rat, rabbit and canine samples, the assay has not been verified for these species.
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Features and Benefits
- Unparalleled Sensitivity: The SMC®technology delivers exceptional performance in quantifying IL-13 in human serum and plasma, enabling precise measurements.
- Enhanced Research Insights: The ability to detect low levels of IL-13 provides valuable insights into immune responses, inflammation, and disease mechanisms.
- Cost-Effective: By allowing for the detection of low-abundance cytokines, these assays can reduce the need for larger sample volumes and repeated testing, ultimately saving time and resources.
- Streamlined Laboratory Operations: The kit′s design and features enhance workflow efficiency, allowing researchers to focus on data generation rather than preparation.
General description
Interleukin 13 (IL-13) is secreted by a number of cells including T helper cells, CD4 cells and a various white blood cells and is thought to be a mediator of allergic inflammation in many tissues via the induction of IgE synthesis by B cells. Although primarily associated with the induction of airway disease, IL-13 has also been shown to inhibit the production of proinflammatory cytokines by monocytes and macrophages suggesting it has important anti-inflammatory properties.
Packaging
96 well assay
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
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Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.
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