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Merck
CN

03-0159-00

SMC ®人IL-17A高灵敏度试剂盒

Used for ultrasensitive quantification of Human IL-17A in human serum and plasma

别名:

IL-17A Single Molecule Counting Kit, IL-17A immunoassay kit, IL-17A ultra-sensitive immunoassay, Interleukin-17A immunoassay kit

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关于此项目

NACRES:
NA.84
UNSPSC Code:
12161503
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产品名称

SMC ®人IL-17A高灵敏度试剂盒, Used for ultrasensitive quantification of Human IL-17A in human serum and plasma

manufacturer/tradename

SMC®

product line

SMC®

usage

 kit sufficient for 96 wells

species reactivity

human

technique(s)

single molecule counting: suitable

input

plasma (K2 EDTA)
serum

UniProt accession no.

compatibility

for use with FemtoQuest and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

Biochem/physiol Actions

可以检测到小鼠、大鼠、马、犬和兔样品。 尽管可以检测到IL-17A,但尚未对这些物种进行验证。

Disclaimer

我们的产品仅用于研究目的,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用对人类或动物。

General description

SMC® 人IL-17A高灵敏度免疫分析试剂盒包含进行分析所需的所有试剂。该测定采用以标准孔板形式配置的标准免疫测定工作流程。

测定方案与现有的夹心ELISA方法相似,但有两个主要区别:
1)洗脱缓冲液破坏夹心结构,分离标记的检测抗体以进行定量。
2)Erenna 和SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术对分析物进行检测。

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Packaging

96 well assay

Analysis Note

  • Sensitivity: LLOQ 70 fg/mL* (SMCxPRO® instrument
  • Standard Curve Range: 20-60,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 106% Plasma: 93%
  • Recovery: Serum: 92% Plasma: 103%

* Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & Immunology Inflammatory Disease Immune Response Autoimmune Disease

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

  • Unmatched Detection Capability: Utilizing SMC® technology, this assay offers superior performance in quantifying IL-17A in human serum and plasma, ensuring precise and reliable measurements.
  • Advance Autoimmune & Inflammatory Disease Research: IL-17A is a key cytokine in Th17-mediated immunity. This assay supports studies in psoriasis, rheumatoid arthritis, IBD, and other chronic inflammatory conditions.
  • Enable Early Biomarker Discovery: High sensitivity allows detection of subclinical cytokine shifts, supporting early-stage biomarker identification and therapeutic target validation.
  • Improve Data Quality & Confidence: Low background and high signal-to-noise ratio ensure robust, publication-ready data.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

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实验方案

To determine protein content, the Warburg-Christian method refers to measuring protein samples at 280 nm using a spectrophotometer.

相关内容

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Learn how immunoassays are used in cosmetics and personal care research to discover potential harmful effects of cosmetics products, and assess markers of inflammation, sensitization, aging, and tissue regeneration among others.

Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.

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