03-0161-00
SMC® Human IL-4 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-4 in human serum and plasma
别名:
IL-4 Single Molecule Counting Kit, interleukin-4 immunoassay
登录 查看组织和合同定价。
选择规格
变更视图
关于此项目
NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with FemtoQuest™ and SMCxPRO® instruments
产品名称
SMC® Human IL-4 High Sensitivity Immunoassay Kit,
description
Used for ultrasensitive quantification of Human IL-4 in human serum and plasma
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
plasma (K2 EDTA)
serum
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
shipped in
wet ice
storage temp.
2-8°C
General description
Interleukin-4 (IL-4) is a cytokine primarily produced by activated T cells, particularly Th2 cells, and plays a crucial role in the immune response. It is essential for the differentiation of B cells, promoting the production of antibodies, and is involved in the regulation of various immune functions, including the enhancement of IgE production, which is significant in allergic responses. Additionally, IL-4 is implicated in the pathogenesis of several diseases, including asthma and other allergic conditions.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Exceptional Sensitivity: The SMC®technology provides outstanding performance in measuring IL-4 levels in human serum and plasma, allowing for accurate quantification.
- Complete, Ready-to-Use Kit: Includes IL-4 coated beads, detection antibody, standards, buffers, and wash solutions—everything needed for a seamless assay run on the FemtoQuest™ system.
- Advance Allergy & Immune Response Studies: IL-4 is central to Th2 cell differentiation, B cell activation, and IgE production. This assay supports research in asthma, atopic dermatitis, and allergic inflammation.
- Detect Early Immune Shifts: With femtogram-level sensitivity, you can identify subclinical cytokine changes—ideal for early-stage biomarker discovery and therapeutic development.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 10-10,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 95% Plasma: 91%
- Recovery: Serum: 92% Plasma: 96%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although IL-4 was detectable in non-human primate, rat, equine, feline and canine samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3