03-0168-00
SMC® Human IL-5 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IL-5 in human serum and plasma
别名:
IL-5 Single Molecule Counting kit, IL-5 immunoassay kit, IL-5 ultrasensitive immunoassay, interleukin-5 immunoassay
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NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
ELISA: suitable, single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with FemtoQuest™ and SMCxPRO® instruments (validated)
technique(s)
ELISA: suitable, single molecule counting: suitable
input
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments (validated)
shipped in
wet ice
storage temp.
2-8°C
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
General description
Interleukin-5 (IL-5) is a cytokine primarily produced by activated T cells, particularly Th2 cells, and plays a pivotal role in the regulation of eosinophil differentiation, activation, and survival. It is essential for the immune response against parasitic infections and is also implicated in allergic reactions and asthma, where elevated levels of IL-5 contribute to eosinophilic inflammation. Understanding IL-5′s functions is crucial for developing targeted therapies for various allergic and inflammatory diseases.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Ultra-High Sensitivity: This IL-5 assay kit offers exceptional sensitivity, allowing researchers to detect low concentrations of IL-5 in biological samples, which is crucial for studying subtle changes in immune responses.
- Accurate Quantification: With precise measurement capabilities, the kit enables accurate quantification of IL-5 levels, facilitating reliable data collection for research on allergic diseases, asthma, and eosinophilic disorders.
- Cost-Effective Research Tool: By enabling the early detection of IL-5 and reducing the need for extensive follow-up studies, this high-sensitivity assay kit can help optimize research budgets while providing valuable insights into immune function.
- SMC Technology Advantage: The incorporation of SMC technology allows for unprecedented sensitivity and accuracy in IL-5 detection, making it a game-changer for researchers aiming to uncover critical insights into immune system dynamics.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 10-50,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 106% Plasma: 111%
- Recovery: Serum: 98% Plasma: 100%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Other Notes
Although IL-5 was detectable in non-human primate, canine, rat, and mouse plasma, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B
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