03-0171-00
SMC® Human Brain-Derived Neurotrophic Factor (BDNF) High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human BDNF in human serum, plasma, and cerebrospinal fluid (CSF)
别名:
Abrineurin immunoassay kit, BDNF Single Molecule Counting Kit, BDNF ultra-sensitive immunoassay
产品名称
SMC® Human Brain-Derived Neurotrophic Factor (BDNF) High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human BDNF in human serum, plasma, and cerebrospinal fluid (CSF)
technique(s)
single molecule counting: suitable
product line
SMC®
usage
kit sufficient for 96 wells
manufacturer/tradename
SMC®
input
serum
cerebrospinal fluid (CSF)
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
relevant disease(s)
Alzheimer′s disease
shipped in
wet ice
storage temp.
2-8°C
General description
BDNF plays a significant role in neurological disorders and neurodegenerative diseases. Reduced levels of BDNF have been associated with conditions like Alzheimer′s disease, Parkinson′s disease, and depression. Low BDNF levels can lead to neuronal atrophy, impaired synaptic function, and increased vulnerability to neuroinflammation, exacerbating disease progression. Conversely, enhancing BDNF signaling has been shown to promote neuroprotection, improve cognitive function, and support recovery in animal models of neurodegeneration.
Understanding BDNF′s function and its involvement in neuroinflammation and neurodegenerative processes is crucial for developing therapeutic strategies aimed at enhancing BDNF signaling to improve outcomes for neurological disorders.
Legal Information
Analysis Note
- Sensitivity: LLOQ 40 fg/mL* (SMCxPRO® Instrument
- Standard Curve Range: 20-100,000 fg/mL
- Intra-assay CV: <10%
- Inter-assay CV: <15%
- Linearity: Serum: 85% Plasma: 102%
- Recovery: Serum: 90% Plasma: 96% CSF: 98%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Biochem/physiol Actions
Disclaimer
Features and Benefits
- Ultra-Sensitive Measurement: Accurately measures BDNF at femtogram/mL concentrations in serum, plasma, or CSF.
- Enhanced Signal Clarity: Improves the signal-to-noise ratio, minimizing background noise for consistent assay results.
- Intuitive Workflow: Employs a familiar sandwich immunoassay design, facilitating easy adoption for researchers trained in ELISA.
- Ready for Automation: Designed to integrate with automated liquid handling systems, streamlining processes and boosting laboratory productivity.
- Comprehensive Support: Supported by experienced field scientists and technical experts.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
target_organs
Respiratory Tract
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
法规信息
相关内容
通过适合的免疫检测产品，探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。
在强大的SMCxPRO®检测平台上，采用单分子计数(SMC®)高灵敏度免疫检测试剂盒，准确可靠地检测健康和病患来源的主要神经学蛋白分析物，进行神经科学研究。分析各种神经科学生物标志物，如神经丝蛋白轻链(NF-L)、胶质纤维酸性蛋白(GFAP)、Tau蛋白、β-淀粉样蛋白等。
Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.
Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持