SMC^® Human IL-17A/F Heterodimer High Sensitivity Immunoassay Kit

Interleukin-17A/F (IL-17A/F) is a heterodimeric cytokine formed by the combination of IL-17A and IL-17F subunits, both of which are produced primarily by Th17 cells. This cytokine plays a significant role in mediating inflammatory responses and is involved in the recruitment of neutrophils and other immune cells to sites of inflammation. IL-17A/F is implicated in various autoimmune diseases and chronic inflammatory conditions, highlighting its potential as a therapeutic target for managing such disorders.

Inflammatory Disease / Immune Response / Autoimmune Disease

96 well assay

• Sensitivity: LLOQ 2,340 fg/mL* (SMCxPRO^® Instrument)
• Standard Curve Range: 590-600,000 fg/mL
• Intra-assay CV: <15%
• Inter-assay CV: <20%
• Linearity: Serum: 106% Plasma: 111%
• Recovery: Serum: 101% Plasma: 88%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.

Although IL-17A/F Heterodimer was detectable in non-human primates, monkey and canine samples, the assay has not been verified for these species.

SMC is a registered trademark of Singulex

SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.