跳转至内容
Merck
CN

03-0180-00

SMC® Human VEGF-A High Sensitivity Immunoassay Kit

Used for ultrasensitive quantification of Human VEGF-A in human serum and plasma

别名:

VEGF-A Single Molecule Counting Kit, VEGF-A ultra-sensitive immunoassay, Vascular endothelial growth factor A immunoassay kit, Vascular permeability factor immunoassay kit

登录 查看组织和合同定价。

选择尺寸

关于此项目

NACRES:
NA.84
UNSPSC Code:
12161503

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

SMC® Human VEGF-A High Sensitivity Immunoassay Kit, Used for ultrasensitive quantification of Human VEGF-A in human serum and plasma

product line

SMC®

usage

 kit sufficient for 96 wells

species reactivity

human

manufacturer/tradename

SMC®

technique(s)

single molecule counting: suitable

input

serum
plasma (K2 EDTA)

UniProt accession no.

P15692

compatibility

for use with FemtoQuest™ and SMCxPRO® instruments

shipped in

wet ice

storage temp.

2-8°C

相关类别

Packaging

96 well assay

Legal Information

SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany

Biochem/physiol Actions

Although VEGF-A was detectable in non-human primate, canine and feline samples, the assay has not been verified for these species.

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Analysis Note

  • Sensitivity: LLOQ 200 fg/mL* (SMCxPRO® Instrument)
  • Standard Curve Range: 100-100,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: Serum: 106% Plasma: 105%
  • Recovery: Serum: 103% Plasma: 93%
*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Inflammation & ImmunologyInflammatory DiseaseImmune ResponseAutoimmune Disease

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

  • Femtogram-Level Sensitivity for VEGF-A Detection: Enables ultrasensitive quantification of VEGF-A, critical for detecting early-stage angiogenic signaling in cancer, wound healing, and vascular disorders.
  • High Specificity for VEGF-A Isoforms: No cross-reactivity with VEGF-B, VEGF-C, or VEGF-D. Ensures accurate measurement of VEGF-A, the most potent pro-angiogenic isoform, without interference from related growth factors.
  • Critical Tool for Cancer and Angiogenesis Research: Enables monitoring of VEGF-A expression in tumor microenvironments, supporting studies on tumor progression, metastasis, and response to anti-angiogenic therapies.

General description

Vascular Endothelial Growth Factor A (VEGF-A) is a crucial signaling protein that promotes the growth of blood vessels (angiogenesis) in various physiological and pathological processes. It is primarily produced by endothelial cells and is involved in wound healing, embryonic development, and the response to ischemia. Elevated levels of VEGF-A are often associated with tumor growth and metastasis, making it a key target for therapeutic interventions in cancer and other diseases characterized by abnormal blood vessel formation.

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

新产品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

相关内容

Power of High Sensitivity Immunology Assays| SMC® Technology

Use the power of high sensitivity immunology assays with SMC® technology to precisely characterize low-abundant cytokines like those from Th1/Th2 and Th17 cells.

Overview of Ultrasensitive Immunoassay Technology | SMC® Technology

Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.

Protocol- 03-0180-00

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持