03-0186-00
SMC® Human IFN-α2 High Sensitivity Immunoassay Kit
Used for ultrasensitive quantification of Human IFNα2 in human serum and plasma
别名:
IFN-alpha-2 Single Molecule Counting Kit, IFN-alpha-2 immunoassay kit, IFN-alpha-2 ultra-sensitive immunoassay, Interferon alpha-A immunoassay kit
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NACRES:
NA.84
UNSPSC Code:
12161503
Species reactivity:
human
Technique(s):
single molecule counting: suitable
Usage:
kit sufficient for 96 wells
Compatibility:
for use with FemtoQuest™ and SMCxPRO® instruments
产品名称
SMC® Human IFN-α2 High Sensitivity Immunoassay Kit,
description
Used for ultrasensitive quantification of Human IFNα2 in human serum and plasma
product line
SMC®
usage
kit sufficient for 96 wells
species reactivity
human
technique(s)
single molecule counting: suitable
input
serum
plasma (K2 EDTA)
UniProt accession no.
compatibility
for use with FemtoQuest™ and SMCxPRO® instruments
relevant disease(s)
autoimmune diseases
shipped in
wet ice
storage temp.
2-8°C
General description
Human Interferon alpha-2 (IFNa2) is a cytokine belonging to the IFN family exhibiting antiviral, antitumor and antiproliferative effects on immune response. IFNa2 is secreted by viral infected cells and acts to inhibit viral infection. It has been shown to play a role in autoimmune diseases such as lupus and myositis. The mechanisms of action underlying the pathogenic role that IFNa and IFNß play in autoimmunity is not well understood but elucidating their role will lead to a better understanding of these cytokines in chronic inflammation and immunity.
Application
Inflammatory Disease / Immune Response / Autoimmune Disease
Features and Benefits
- Sensitivity that sees what others miss: Captures cytokine fluctuations that standard ELISAs overlook, perfect for subtle immune shifts.
- Track Early Antiviral Responses: IFN-α2 is a key player in innate immunity; this kit helps detect its earliest signals in viral infection models.
- Advance Autoimmune Disease Research: Ideal for studying IFN-α2’s role in conditions like lupus, myositis, and other chronic inflammatory diseases.
- Wide Dynamic Range: Accurately quantifies IFN-α2 across a broad concentration spectrum, suitable for both baseline and elevated immune responses.
Packaging
96 well assay
Analysis Note
- Sensitivity: LLOQ 60 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 15-80,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 90% Plasma: 102%
- Recovery: Serum: 102% Plasma: 96%
Other Notes
Although IFN-α2 was detectable in rat, pig, non-human primate, canine, and feline samples, the assay has not been verified for these species.
Legal Information
FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Danger
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - ED ENV 1 - Eye Irrit. 2 - Repr. 1B