03-0196-00
SMC® Human Total α-synuclein High Sensitivity Immunoassay Kit
Uses 100 µL per well of 1:200 diluted serum or plasma samples, or 1:10 diluted cerebrospinal fluid (CSF) samples.
别名:
Human α-synuclein, α-synuclein, Human total-α-synuclein, a-synuclein, total-a-synuclein
描述
0.49-3.91pg/mL, refer to CoA for lot-specific LLOQ
产品线
SMC®
种属反应性
canine, rat, feline, mouse
制造商/商品名称
SMC®
assay range
sensitivity: 1.95 pg/mL
(LLOQ of Total α-synuclein)
inter-assay cv: 14%
intra-assay cv: 9%
(five normal plasma samples run in triplicate by 3 different operators on 3 different days)
技术
single molecule counting: suitable
一般描述
1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification.
2) The Erenna and SMCxPRO® immunoassay systems detect analytes using Single Molecule Counting (SMC®) technology.
应用
生化/生理作用
Specificity to the following species samples were tested with the following results:
Monkey – 100%
Cat – 100%
Rat – 100%
Mouse – 100%
Beagle – 100%
Cross Reactivity
Cross-reactivity to the following analytes were tested with the following results:
Tau – 0%UCHL1 – 0%
β-synuclein – 0%
γ-synuclein – 0%
Accuracy
CSF Recovery: 5 CSF samples spiked with average recovery of 96% and a range of 90-102%
Serum Recovery: 4 serum samples spiked with average recovery of 96% and a range of 93-98%
Plasma Recovery: 4 plasma samples spiked with average recovery of 96% and a range of 93-97%
包装
分析说明
- Sensitivity: LLOQ 1,950 fg/mL* (SMCxPRO® Instrument)
- Standard Curve Range: 490-500,000 fg/mL
- Intra-assay CV: <15%
- Inter-assay CV: <20%
- Linearity: Serum: 113% Plasma: 118% CSF: 102%
- Recovery: Serum: 96% Plasma: 96% CSF: 96%
其他说明
- Assay Buffer
- Total α-synuclein Coated Beads
- Standard Diluent
- Total α-synuclein Detection Antibody
- Total α-synuclein Standard
- 10X Wash Buffer
- Buffer D
- Elution Buffer B
- This new streamline kit has the following features:
- Improved options for sample prep and incubation
- Lyophilization protein standard for uniform shipping and storage condition
- Increased reagent volumes to accommodate automation
- Able to achieve assay specifications on both SMCxPRO® and Erenna.
法律信息
免责声明
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B
储存分类代码
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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