03-32-1501
Z-Phe-Arg -7-酰氨基-4-甲基香豆素，盐酸
Substrate for fluorogenic assay of plasma and glandular kallikreins.
别名:
Z-Phe-Arg -7-酰氨基-4-甲基香豆素，盐酸
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关于此项目
经验公式（希尔记法）:
C33H36N6O6 · xHCl
化学文摘社编号:
分子量:
612.68 (free base basis)
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.83
产品名称
Z-Phe-Arg -7-酰氨基-4-甲基香豆素，盐酸, Substrate for fluorogenic assay of plasma and glandular kallikreins.
InChI key
QNRBQTLUAIXWTG-WMXJXTQLSA-N
InChI
1S/C33H36N6O6.Cl/c1-21-17-29(40)45-28-19-24(14-15-25(21)28)37-30(41)26(13-8-16-36-32(34)35)38-31(42)27(18-22-9-4-2-5-10-22)39-33(43)44-20-23-11-6-3-7-12-23;/h2-7,9-12,14-15,17,19,26-27H,8,13,16,18,20H2,1H3,(H,37,41)(H,38,42)(H,39,43)(H4,34,35,36);/t26-,27
SMILES string
[Cl].N([C@@H](Cc4ccccc4)C(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc2cc3c(cc2)C(=CC(=O)O3)C)C(=O)OCc1ccccc1
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated
color
white to off-white
solubility
5% acetic acid: 1 mg/mL
DMSO: 1 mg/mL
water: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
主要靶
血浆和腺激肽释放酶荧光检测的底物
血浆和腺激肽释放酶荧光检测的底物
产物不与ATP竞争。
可逆：否
细胞渗透性：否
Disclaimer
毒性：刺激性（B）
General description
血浆和腺激肽释放酶荧光检测的底物也可作为组织蛋白酶B、组织蛋白酶L和木瓜蛋白酶的底物。
Other Notes
Morita, T., et al. 1977.J. Biochem.82, 1495.
Z-Phe-Arg-AMC, HCl
Preparation Note
溶解后，等分并冷冻保存（-20°C）。储备溶液在-20°C下可稳定保存至多3个月。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
T Morita et al.
Journal of biochemistry, 82(5), 1495-1498 (1977-11-01)
Twenty peptide-4-methylcoumarin amides (MCA) were newly synthesized and tested as possible substrates for alpha-thrombin, factor Xa, kallikreins, urokinase, and plasmin. These fluorogenic peptides contained arginine-MCA as the carboxyl-terminus. Release of 7-amino-4-methylcoumarin was determined fluorometrically. Of these peptides, the following were
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