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Merck
CN

03-32-5032

MMP-2/MMP-7 Substrate, Fluorogenic

Extremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs).

别名:

MMP-2/MMP-7 Substrate, Fluorogenic

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关于此项目

经验公式(希尔记法):
C49H68N14O15
分子量:
1093.15
NACRES:
NA.83
UNSPSC Code:
12352209
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assay

≥95% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

yellow

solubility

20% acetic acid: 1 mg/mL

fluorescence

λex ~325 nm, λem ~393 nm

shipped in

ambient

storage temp.

−20°C

Quality Level

General description

Extremely sensitive fluorogenic substrate for matrix metalloproteinases (MMPs). Suitable for assessment of total activity in crude preparations by continuous assays (kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M-1sec-1 for MMP-2).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Fluorogenic substrate for matrix metalloproteinases (MMPs)
Product does not compete with ATP.
Reversible: no
kcat/Km = 1.7 x 105 M-1sec-1 for MMP-7 and 6.3 x 105 M⁻¹ sec⁻¹ for MMP-2

Physical form

Supplied as a trifluoroacetate salt.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Knight, C.G., et al. 1992. FEBS Lett. 296, 263.
MCA-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂ ·TFA [Dpa = N-3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl]

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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