03-34-0001
H-Gly-Pro-Arg-Pro-OH
Inhibitor of fibrinogen aggregation and fibrin polymerization.
别名:
H-Gly-Pro-Arg-Pro-OH
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关于此项目
经验公式（希尔记法）:
C18H31N7O5
化学文摘社编号:
分子量:
425.48
UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
SMILES string
N2([C@@H](CCC2)C(=O)O)C(=O)[C@@H](NC(=O)[C@H]1N(CCC1)C(=O)CN)CCCN=C(N)N
InChI
1S/C18H31N7O5/c19-10-14(26)24-8-2-5-12(24)15(27)23-11(4-1-7-22-18(20)21)16(28)25-9-3-6-13(25)17(29)30/h11-13H,1-10,19H2,(H,23,27)(H,29,30)(H4,20,21,22)/t11-,12-,13-/m0/s1
InChI key
WXPZDDCNKXMOMC-AVGNSLFASA-N
assay
≥98% (HPLC)
form
lyophilized
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
technique(s)
protein extraction: suitable
solubility
5% acetic acid: 1 mg/mL
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
Inhibitor of fibrinogen aggregation and fibrin polymerization.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: no
Other Notes
Barnard, M.R., et al. 1999. Transfusion39, 73.
Rijkers, D.T., et al. 1998. Thromb. Res. 89, 161.
Achyuthan, K.E., and Dobson, J.V. 1986. Biochim. Biophys. Acta872, 261.
Rijkers, D.T., et al. 1998. Thromb. Res. 89, 161.
Achyuthan, K.E., and Dobson, J.V. 1986. Biochim. Biophys. Acta872, 261.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Yiyuan Zhang et al.
Thrombosis research, 192, 141-151 (2020-06-02)
Kinase inhibitors can pose bleeding risks as platelet signaling evolves during clotting. Using microfluidics (200 s-1 wall shear rate) to perfuse Factor XIIa-inhibited or thrombin-inhibited whole blood (WB) over collagen ± tissue factor (TF), we explored the potency of the Src family kinase
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