产品名称
Anti-SOCS3 Antibody, clone 1B2, clone 1B2, Upstate®, from mouse
isotype
IgG1
technique(s)
western blot: suitable
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1B2, monoclonal
species reactivity
mouse, human
manufacturer/tradename
Upstate®
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SOCS3(9021)
Analysis Note
Routinely evaluated by immunoblot.
Application
Research Sub Category
Neuroregenerative Medicine
Developmental Neuroscience
Neuroregenerative Medicine
Developmental Neuroscience
This Anti-SOCS3 Antibody, clone 1B2 is validated for use in WB for the detection of SOCS3.
Biochem/physiol Actions
Recognizes SOCS3.
General description
25 kDa
Immunogen
mouse SOCS3 recombinant GST fusion protein encompassing amino acids 2-44.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein G Purified mouse monoclonal IgG in a solution of 50% glycerol, 0.02 M Phosphate buffer, pH 7.6, 0.25 M NaCl, 0.1% sodium azide as a preservative.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Daniel J Ham et al.
American journal of physiology. Endocrinology and metabolism, 310(11), E970-E981 (2016-04-21)
Amino acids, especially leucine, potently stimulate protein synthesis and reduce protein breakdown in healthy skeletal muscle and as a result have received considerable attention as potential treatments for muscle wasting. However, the normal anabolic response to amino acids is impaired
Sam Ansari et al.
Scientific data, 3, 150077-150077 (2016-01-06)
Smoking of combustible cigarettes has a major impact on human health. Using a systems toxicology approach in a model of chronic obstructive pulmonary disease (C57BL/6 mice), we assessed the health consequences in mice of an aerosol derived from a prototype
Evdokia Dimitriadis et al.
Endocrinology, 147(8), 3809-3817 (2006-05-20)
The differentiation of endometrial stromal cells into decidual cells (decidualization) is critical for embryo implantation, but the mechanisms remain poorly defined. Numerous paracrine agents including IL-11 promote human endometrial stromal cell (HESC) decidualization. IL-11 signaling is transduced by the signal
Kate D Sutherland et al.
Oncogene, 23(46), 7726-7733 (2004-09-14)
Suppressor of cytokine signaling (SOCS) proteins have emerged as critical attenuators of cytokine-mediated processes, suggesting a role in the suppression of tumorigenesis. In the ovary and mammary gland, cytokines such as prolactin and IL-6 are important regulators of growth and
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Cabanski, M; Fields, B; Boue, S; Boukharov, N; DeLeon, H; Dror, N; Geertz, M; Guedj et al.
Inflammation Research null
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