04-039
Anti-20S proteasome subunit α2 Antibody, clone MCP21
clone MCP21, Upstate®, from mouse
别名:
HC3, proteasome subunit alpha type 2
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.28
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
MCP21, monoclonal
Application:
IHC, IP, WB
Citations:
8
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
MCP21, monoclonal
species reactivity
human, rabbit, bovine
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
bovine ... Psma2(539141)
human ... PSMA2(5683)
rabbit ... Psma2(100355295)
General description
26 kDa
Immunogen
Human placenta derived proteasomes
Application
Anti-20S proteasome subunit α2 Antibody, clone MCP21 detects level of 20S proteasome subunit α2 & has been published & validated for use in IP, WB, IH.
Research Category
Protein Trafficking
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
Ubiquitin & Ubiquitin Metabolism
Biochem/physiol Actions
Recognizes proteasome subunit alpha type 2.
Physical form
100 µL concentration of 1mg/mL purified ascites in PBS containing 0.01M sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Ascites
Format: Purified
Preparation Note
Stable for 1 year at -20°C from date of shipment for up to 12 months.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Impact of ageing on proteasome structure and function in human lymphocytes
Carrard, Geraldine, et al
The International Journal of Biochemistry & Cell Biology, 35, 728-739 (2003)
G Zhong et al.
The Journal of experimental medicine, 191(9), 1525-1534 (2000-05-03)
We have previously shown that the obligate intracellular pathogen chlamydia can suppress interferon (IFN)-gamma-inducible major histocompatibility complex (MHC) class II expression in infected cells by degrading upstream stimulation factor (USF)-1. We now report that chlamydia can also inhibit both constitutive
Tomasz Klaus et al.
Scientific reports, 6, 30938-30938 (2016-08-04)
Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained
K B Hendil et al.
The Biochemical journal, 305 ( Pt 1), 245-252 (1995-01-01)
The proteasome or multicatalytic endopeptidase from eukaryotic cells consists of at least 14 subunits that fall into two families, alpha and beta. Subunit-specific monoclonal antibodies against ten different subunits of human proteasomes have been produced, together with an antibody that
Tomasz Klaus et al.
Frontiers in immunology, 9, 1096-1096 (2018-06-08)
Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates erythrocytes. IgG3 also triggers the complement cascade. The
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