SUZ12 is a polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility. Component of the PRC2 complex, which methylates ′Lys-9′ and ′Lys-27′ residues of histone H3.

SUZ12

Full length, recombinant human SUZ12.

Anti-SUZ12 Antibody, clone 3C1.2 is a high quality Mouse Monoclonal Antibody for the detection of SUZ12 & has been validated in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Routinely evaluated by immunoblot.

95 kDa

Protein A purified

100 μg of Protein A purified mouse monoclonal IgG1κ in 100 μL of 1X PBS, pH 7, 0.1% Azide.

Format: Purified

2 years at -20°C from date of shipment.

Control
HeLa cell lysate

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