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Merck
CN

04-047

Anti-CUGBP2 Antibody, clone 1H2

clone 1H2, Upstate®, from mouse

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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产品名称

Anti-CUGBP2 Antibody, clone 1H2, clone 1H2, Upstate®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1H2, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_001025076.2
NM_001025077.2
NM_001083591.1
NM_006561.3

UniProt accession no.

O95319

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... CELF2(10659)

Analysis Note

Routinely evaluated by immunoblot.

Application

Research Category
Protein Trafficking
Research Sub Category
RNA Metabolism & Binding Proteins

RNA Binding Protein (RBP)
This Anti-CUGBP2 Antibody, clone 1H2 is validated for use in WB for the detection of CUGBP2.

Biochem/physiol Actions

CuGBP2

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

56 kDa

Immunogen

A synthetic peptide corresponding to amino acids 209-415 of human CuGBP2.

Physical form

100 μg of Protein A purified mouse monoclonal IgG1 in 100μl of 1X PBS, pH 7.0, 0.1% Azide.
Format: Purified
Protein A purified

Preparation Note

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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P Lichtner et al.
Journal of molecular medicine (Berlin, Germany), 80(7), 431-442 (2002-07-12)
Partial monosomy 10p is a rare chromosomal aberration. Patients often show symptoms of the DiGeorge/velocardiofacial syndrome spectrum. The phenotype is the result of haploinsufficiency of at least two regions on 10p, the HDR1 region associated with hypoparathyroidism, sensorineural deafness, and
Cindy Meyer et al.
Molecular cell, 69(4), 622-635 (2018-02-13)
TIA1 and TIAL1 encode a family of U-rich element mRNA-binding proteins ubiquitously expressed and conserved in metazoans. Using PAR-CLIP, we determined that both proteins bind target sites with identical specificity in 3' UTRs and introns proximal to 5' as well as
Gopal Singh et al.
Nucleic acids research, 32(3), 1232-1241 (2004-02-20)
Members of the CUG-BP and ETR-3 like factor (CELF) protein family bind within conserved intronic elements (called MSEs) flanking the cardiac troponin T (cTNT) alternative exon 5 and promote exon inclusion in vivo and in vitro. Here we use a
Debnath Mukhopadhyay et al.
Annals of the New York Academy of Sciences, 1010, 504-509 (2004-03-23)
Posttranscriptional control of gene expression plays a key role in regulating gene expression in cells undergoing apoptosis. Cyclooxygenase-2 (COX-2) is a crucial enzyme in the conversion of arachidonic acid to prostaglandin E2 (PGE(2)) and is significantly upregulated in many types

相关内容

RNA-Binding Protein Immunoprecipitation

All eukaryotic organisms require tight regulation of gene expression for complex processes such as development, differentiation, cell specification, and responses to environmental stimuli. Many genes are regulated post-transcriptionally, in addition to transcriptional mechanisms of gene regulation. RNA-binding proteins (RBPs) are essential for post-transcriptional gene regulation, linking transcription and translation in many processes including transcription, splicing, export, rate of translation and turnover. In all of these events, RBPs coordinate regulation of the amount of protein produced from mRNA transcripts.

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