产品名称
Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5, clone 19G5, Upstate®, from mouse
isotype
IgG1
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
19G5, monoclonal
species reactivity
canine, rat, mouse, human
manufacturer/tradename
Upstate®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pTyr1112)
Quality Level
Gene Information
human ... ERBB2(2064)
mouse ... Erbb2(13866)
Analysis Note
Control
Includes EGF treated SKOV-3 lysate as a positive control
Includes EGF treated SKOV-3 lysate as a positive control
Routinely evaluated by immunoblot.
Application
Detect phosho-erbB2/Her2 (Tyr1112) using this Anti-phosho-erbB2/Her2 (Tyr1112) Antibody, clone 19G5 validated for use in ELISA & WB.
Biochem/physiol Actions
Recognizes phosphorylated domain of erbB2/Her2 on Tyrosine 1112
General description
185 kDa
Immunogen
KLH-conjugated synthetic peptide encompassing the surrounding amino acids of Tyr1112 in human erbB2/Her2
Physical form
Format: Purified
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
L N Klapper et al.
Cancer research, 60(13), 3384-3388 (2000-07-26)
Overexpression of HER-2/ErbB-2, a homologue of the epidermal growth factor receptor, is associated with poor prognosis, and an ErbB-2-specific antibody is therapeutic when administered to patients with metastatic breast cancer. To understand the mechanism underlying immunotherapy, we concentrated on antibody-
Leonie W Wahjudi et al.
International journal of cancer, 148(6), 1438-1451 (2020-09-20)
DNA sequencing and RNA sequencing are increasingly applied in precision oncology, where molecular tumor boards evaluate the actionability of genetic events in individual tumors to guide targeted treatment. To work toward an additional level of patient characterization, we assessed the
Erin-Mai F Lim et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(9), E1707-E1716 (2017-02-01)
AlphaB-crystallin (αBC) is a small heat shock protein that is constitutively expressed by peripheral nervous system (PNS) axons and Schwann cells. To determine what role this crystallin plays after peripheral nerve damage, we found that loss of αBC impaired remyelination
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持