04-959
Anti-Retinoid-Related Orphan Receptor γ T Antibody, clone RORg2
clone RORg2, from hamster(Armenian)
别名:
RAR-related orphan receptor C, RAR-related orphan receptor gamma, retinoic acid-binding receptor gamma, nuclear receptor ROR-gamma, retinoid-related orphan receptor gamma, Nuclear receptor RZR-gamma, RZR-GAMMA, Nuclear receptor subfamily 1 group F member
产品名称
Anti-Retinoid-Related Orphan Receptor γ T Antibody, clone RORg2, clone RORg2, from hamster(Armenian)
biological source
hamster (Armenian)
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
RORg2, monoclonal
species reactivity
mouse
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Rorc(19885)
Analysis Note
Control
EL4 cell lysate
EL4 cell lysate
Evaluated by Western Blot in EL4 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected Retinoid-Related Orphan Receptor γ T (RORγT) in 10 µg of EL4 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected Retinoid-Related Orphan Receptor γ T (RORγT) in 10 µg of EL4 cell lysate.
Application
Detect Retinoid-Related Orphan Receptor γ T using this Anti-Retinoid-Related Orphan Receptor γ T Antibody, clone RORg2 validated for use in WB, FC & IF.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Inflammation & Autoimmune Mechanisms
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Retinoid-related orphan receptor-gamma t (RORγT) is one of two RORγ isoforms belonging to the nuclear hormone receptor family and contains a single nuclear receptor DNA-binding domain. RORγT is a negative regulator of TNFDF6/FASL expression and T-cell production of IL2. The upregulation of RORγT is a requirement for TH17 cell differentiation. Inhibition of RORγT is induced by TGF-β’s interaction with Foxp3. Expression is observed mainly in immature thymocytes, and, during fetal development, is found exclusively in lymphoid-inducer (LTi) cells.
~52 kDa observed
Immunogen
Epitope: Unknown
Histidine-tagged recombinant protein corresponding to mouse Retinoid-Related Orphan Receptor γ T (RORγT).
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein G Purified
Purified hamster monoclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Chun-Sheng Bi et al.
Cell proliferation, 53(6), e12827-e12827 (2020-05-15)
Previously, we found that by regulating T helper (Th) cell polarization, calcitriol intervention inhibited lipopolysaccharide (LPS)-induced alveolar bone loss in an animal periodontitis model, but the underlying cellular events remain unknown. In this study, mouse Th cells were incubated in
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