Quality Level
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
19B2, monoclonal
species reactivity
human, rat
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... FGFR1(2260)
General description
110 kDa
Immunogen
E. coli fusion protein corresponding to amino acids 23-325 of human FGF receptor beta (Flg)
Application
Anti-FGFR1 Antibody, clone 19B2 detects level of FGFR1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
Biochem/physiol Actions
extra cellular domain for both (alpha and beta) human FGF receptor
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide
Format: Purified
Protein G Chromatography
Preparation Note
2 years at -20°C or 2 months at 4°C
Analysis Note
routinely evaluated in sFGFR-1 (obtained from Alexis Biochemicals, Catalog # SFC-015)
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms.
Xu, J, et al.
The Journal of Biological Chemistry, 267, 17792-17803 (1992)
Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs
Saffell, J. L., et al
Neuron, 18, 231-242 (1997)
Up-regulation of fibroblast growth factor receptor-1 in lens epithelial cells paralleled by growth stimulation.
T Marunouchi, H Hosoya, T Morioku, T Mori, Y Majima, M Kousaka
Experimental Eye Research null
Y Mazaki et al.
Molecular biology of the cell, 12(3), 645-662 (2001-03-17)
Paxillin acts as an adaptor protein in integrin signaling. We have shown that paxillin exists in a relatively large cytoplasmic pool, including perinuclear areas, in addition to focal complexes formed at the cell periphery and focal adhesions formed underneath the
Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo.
M Wagner, M E Lopez, M Cahn, M Korc
Gastroenterology null
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