05-1567
Anti-p120 Catenin Antibody, clone 15D2
clone 15D2, from mouse
别名:
Cadherin-associated Src substrate, catenin (cadherin-associated protein), delta 1, catenin, delta 1, p120 catenin
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
15D2, monoclonal
Application:
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Species reactivity:
mouse, human
Citations:
5
Technique(s):
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
immunocytochemistry: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-p120 Catenin Antibody, clone 15D2, clone 15D2, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
15D2, monoclonal
species reactivity
mouse, human
species reactivity (predicted by homology)
rat
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
western blot: suitable
isotype
IgG1κ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CTNND1(1500)
Analysis Note
Control
Hela cell lysate.
Hela cell lysate.
Evaluated by Western Blot on Hela cell lysate.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.
Western Blot Analysis: 1 g/mL of this antibody detected p120 Catenin in lysate from Hela cells.
Application
Immunocytochemistry:
Research Category
Signaling
Signaling
Research Sub Category
Transcription Factors
Transcription Factors
Use Anti-p120 Catenin Antibody, clone 15D2 (mouse monoclonal antibody) validated in WB, ICC, FC to detect p120 Catenin also known as Cadherin-associated Src substrate ,catenin (cadherin-associated protein) delta 1.
Biochem/physiol Actions
Recognizes p120 Catenin
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
90-120 kDa
p120 Catenin is a cadherin-associated protein that binds intracellular proteins, such as the small GTPase, RhoA, and controls E-cadherin funcation and stability. Proteins of the p120 family and their isoforms are expressed in cells via alternative splicing, and all of them are essential for HGF signaling to Rac1.
Immunogen
Epitope: C-terminus
Recombinant fusion protein derived from the C-terminus of murine p120
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-237
Physical form
Format: Purified
Protein G Chromatography
Purified mouse monoclonal in 0.1M Tris-Glycine (pH 7.4), 150mM NaCl and 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Hiromi Sato et al.
PLoS neglected tropical diseases, 11(7), e0005830-e0005830 (2017-07-28)
Pathogenic Leptospira transmits from animals to humans, causing the zoonotic life-threatening infection called leptospirosis. This infection is reported worldwide with higher risk in tropical regions. Symptoms of leptospirosis range from mild illness to severe illness such as liver damage, kidney
Dulari Jayawardena et al.
Cellular and molecular gastroenterology and hepatology, 15(4), 903-919 (2022-12-20)
Down-regulation of chloride transporter SLC26A3 or down-regulated in adenoma (DRA) in colonocytes has recently been linked to the pathogenesis of ulcerative colitis (UC). Because exaggerated immune responses are one of the hallmarks of UC, these current studies were undertaken to
Lorena de la Fuente et al.
Genome biology, 21(1), 119-119 (2020-05-20)
Recent advances in long-read sequencing solve inaccuracies in alternative transcript identification of full-length transcripts in short-read RNA-Seq data, which encourages the development of methods for isoform-centered functional analysis. Here, we present tappAS, the first framework to enable a comprehensive Functional
Lindy J Pence et al.
International journal of molecular sciences, 22(3) (2021-02-03)
Inflammatory breast cancer is a highly aggressive form of breast cancer that forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. These cancers express high levels of E-cadherin, the major mediator of adherens junctions, which enhances formation of
Joyce Nair-Menon et al.
International journal of molecular sciences, 21(7) (2020-04-11)
The RNA interference (RNAi) machinery is an essential component of the cell, regulating miRNA biogenesis and function. RNAi complexes were thought to localize either in the nucleus, such as the microprocessor, or in the cytoplasm, such as the RNA-induced silencing
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