生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
7G7/B6, monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
dot blot: suitable
immunocytochemistry: suitable
同位素/亚型
IgG2a
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... IL2RA(3559)
一般描述
55 kDa
免疫原
Whole cells expressing human IL-2 Receptor α
应用
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
This Anti-IL-2 Rα Antibody, clone 7G7/B6 is validated for use in DB, IC for the detection of IL-2 Rα.
生化/生理作用
Recognizes interleukin-2 receptor.
外形
Protein G Purified
Format: Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide as a preservative.
制备说明
Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C
分析说明
Control
Lung tissue
Lung tissue
routinely evaluated on ice cold ethanol/acetic acid [95:5] fixed phytohemagglutinin (PHA)-treated Jurkat T lymphocytes
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3
储存分类代码
11 - Combustible Solids
WGK
WGK 1
Sabine S Lange et al.
PLoS genetics, 12(1), e1005759-e1005759 (2016-01-05)
DNA polymerase ζ (pol ζ) is exceptionally important for maintaining genome stability. Inactivation of the Rev3l gene encoding the polymerase catalytic subunit causes a high frequency of chromosomal breaks, followed by lethality in mouse embryos and in primary cells. Yet
Benjamin C Jennings et al.
FEBS letters, 595(13), 1758-1767 (2021-05-16)
The SARS-CoV-2 spike glycoprotein (spike) mediates viral entry by binding ACE2 receptors on host cell surfaces. Spike glycan processing and cleavage, which occur in the Golgi network, are important for fusion at the plasma membrane, promoting both virion infectivity and
P D Tahiliani et al.
The Journal of biological chemistry, 272(12), 7892-7898 (1997-03-21)
Integrin-mediated adhesion of cells to extracellular matrix proteins triggers a variety of intracellular signaling pathways including a cascade of tyrosine phosphorylations. In many cell types, the cytoplasmic focal adhesion tyrosine kinase, FAK, appears to be the initial protein that becomes
A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.
Rubin, L A, et al.
Hybridoma, 4, 91-102 (1985)
K S Lai et al.
The Journal of biological chemistry, 270(42), 25028-25036 (1995-10-20)
Signal transduction of cytokine receptors is mediated by the JAK family of tyrosine kinases. Recently, the kinase partners for the interleukin (IL)-2 receptor have been identified as JAK1 and JAK3. In this study, we report the identification of splice variants
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