05-1938
Anti-G3BP1 Antibody, clone 14E5-G9
clone 14E5-G9, from mouse
别名:
ATP-dependent DNA helicase VIII, GAP SH3 domain-binding protein 1, GAP binding protein, GTPase activating protein (SH3 domain) binding protein 1, Ras-GTPase-activating protein SH3-domain-binding protein, RasGAP-associated endoribonuclease G3BP
生物来源
mouse
质量水平
偶联物
unconjugated
抗体产品类型
primary antibodies
克隆
14E5-G9, monoclonal
种属反应性
human
技术
immunocytochemistry: suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... G3BP1(10146)
一般描述
G3BP1 (Ras-GTPase activating protein SH3-domain binding protein 1) directly associates with SH3 domains of GTPase activating proteins (GAPs). It was first discovered by its binding to RasGAP. G3BPs have been shown to be involved in a number of mitogenic signaling pathways. G3BP1 is also known to be over expressed in many human cancers (Kim, 2007) and its expression appears to be inversely correlated with PTEN expression (Kim, 2007). Interestingly, G3BP1, along with G3BP2, has been shown to bind to the C-terminus of p53, playing a crucial role in its activity (Kim, 2007). Furthermore, the G3BPs have two traditional RNA binding motifs.
52 kDa
免疫原
GST-tagged recombinant protein corresponding to human G3BP1.
应用
Anti-G3BP1 Antibody, clone 14E5-G9 is an antibody against G3BP1 for use in WB & IC.
Research Sub Category
RNA Metabolism & Binding Proteins
G-proteins
RNA Metabolism & Binding Proteins
G-proteins
生化/生理作用
This antibody recognizes G3BP1.
外形
Format: Purified
分析说明
Evaluated by Western Blot in K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
Western Blot Analysis: 0.1 µg/mL of this antibody detected G3BP1 on K562 cell lysate.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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