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Merck
CN

05-22-3838

BQ-788, Sodium Salt

别名:

BQ-788, Sodium Salt, N- cis-2,6-Dimethylpiperidinocarbonyl-L-γ-MeLeu-D-Trp(MeOCO)-D-Nle-OH, Na

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关于此项目

经验公式（希尔记法）:
C34H50N5NaO7
分子量:
663.78
NACRES:
NA.28
UNSPSC Code:
12352200
Assay:
≥95% (HPLC)
Form:
lyophilized solid
Quality level:
100
Storage condition:
OK to freeze, desiccated

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assay

≥95% (HPLC)

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

white to off-white

solubility

0.01% NH4OH: 1 mg/mL, DMSO: 2 mg/mL, methanol: water (3:1): 2 mg/mL

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

A highly selective and competitive ETB receptor antagonist (IC50 = 1.2 nM).
Highly selective ETB-receptor antagonist (IC50 = 1.2 nM).

Biochem/physiol Actions

Cell permeable: no
Primary Target
ETB-receptor antagonist
Product does not compete with ATP.
Reversible: no
Target IC50: 1.2 nM as ETB-receptor antagonist

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). DMSO and Methano:H₂O stock solutions are stable for up to 2 months at -20°C.

Other Notes

Okada, M., and Nishikibe, M. 2002. Cardiovasc. Drug Reviews20, 53.
Taniai, H., et al. 2001. Hepatology33, 894.
Fukuroda, T., et al. 1994. Biochem. Biophys. Res. Commun.199, 1461.
Ishikawa, K., et al. 1994. Proc. Natl. Acad. Sci. USA91, 4892.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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