05-337
Anti-MARCKS Antibody, clone 2F12
ascites fluid, clone 2F12, Upstate®
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
2F12, monoclonal
Application:
immunoprecipitation (IP)
western blot
western blot
Species reactivity:
bovine, human
Citations:
4
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-MARCKS Antibody, clone 2F12, ascites fluid, clone 2F12, Upstate®
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
2F12, monoclonal
species reactivity
bovine, human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MARCKS(4082)
General description
none given
Biochem/physiol Actions
MARCKS
Immunogen
Purified recombinant human MARCKS; Epitope mapped to the carboxyl-terminal.
Physical form
Ascites
mouse ascites containing 0.05% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Analysis Note
routinely evaluated by immunoblot on bovine brain extract
Application
Anti-MARCKS Antibody, clone 2F12 detects level of MARCKS & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Cytoskeletal Signaling
Cytoskeletal Signaling
Preparation Note
6 months at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Shijing Fang et al.
American journal of physiology. Lung cellular and molecular physiology, 304(8), L511-L518 (2013-02-05)
Myristoylated alanine-rich C kinase substrate (MARCKS) protein has been recognized as a key regulatory molecule controlling mucin secretion by airway epithelial cells in vitro and in vivo. We recently showed that two intracellular chaperones, heat shock protein 70 (HSP70) and
Jin-Ah Park et al.
The American journal of pathology, 171(6), 1822-1830 (2007-12-07)
Mucin hypersecretion is a major pathological feature of many respiratory diseases, yet cellular mechanisms regulating secretion of mucin have not been fully elucidated. Previously, we reported that mucin hypersecretion induced by human neutrophil elastase involves activation of protein kinase C
20-Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C
Lange, A., et al
The Journal of Biological Chemistry, 272, 27345-27352 (1997)
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