Merck
CN
所有图片(1)

文件

05-351

Sigma-Aldrich

Anti-Fas Antibody, clone 7C10

clone 7C10, Upstate®, from rat

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eCl@ss:
32160702
NACRES:
NA.41

生物来源

rat

质量水平

100

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

7C10, monoclonal

种属反应性

mouse, bovine

制造商/商品名称

Upstate®

技术

immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG2a

NCBI登记号

NM_152877

UniProt登记号

P25445

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

bovine ... Fas(282488)

特异性

Fas

免疫原

recombinant protein containing the cytoplasmic domain of mouse Fas

应用

Anti-Fas Antibody, clone 7C10 is an antibody against Fas for use in IP & WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

质量

routinely evaluated on RIPA lysates of mouse 3T3/A31 fibroblasts or membrane preparations of bovine brain

目标描述

45kDa

外形

Protein G Chromatography
0.1 M Tris-glycine, 0.15 M NaCl, pH 7.4 with 0.05% sodium azide
Format: Purified

储存及稳定性

2 years at -20°C

分析说明

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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Progesterone is a suppressor of apoptosis in bovine luteal cells.
Okuda, K; Korzekwa, A; Shibaya, M; Murakami, S; Nishimura, R; Tsubouchi et al.
Biology of reproduction null
Murugesan V S Rajaram et al.
PloS one, 4(11), e7919-e7919 (2009-11-26)
Francisella tularensis infects macrophages and escapes phago-lysosomal fusion to replicate within the host cytosol, resulting in host cell apoptosis. Here we show that the Fas-mediated death pathway is activated in infected cells and correlates with escape of the bacterium from
Fas-mediated apoptosis is suppressed by calf serum in cultured bovine luteal cells.
Dariusz J Skarzynski, Masami Shibaya, Yukari Tasaki, Anna Korzekwa, Shuko Murakami et al.
Reproductive Biology null
Regulation of luteal function and corpus luteum regression in cows: hormonal control, immune mechanisms and intercellular communication.
D J Skarzynski,G Ferreira-Dias,K Okuda
Reproduction in domestic animals = Zuchthygiene null
Eszter Doma et al.
FEBS letters, 584(5), 1033-1040 (2010-02-09)
The activation of cysteine-aspartic proteases or caspases and the dynamic arrangement of cytoskeletal components are crucial during apoptosis. Here we describe the fate of Fas downstream of the FasL-induced internalization step, including formation of caspase-dependent SDS-stable Fas complexes, which is
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