05-372
Anti-GRB2 Antibody, clone 3F2
clone 3F2, Upstate®, from mouse
别名:
Anti-ASH, Anti-EGFRBP-GRB2, Anti-Grb3-3, Anti-MST084, Anti-MSTP084, Anti-NCKAP2
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
3F2, monoclonal
种属反应性
bovine, mouse, hamster, rat, human
制造商/商品名称
Upstate®
技术
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... GRB2(2885)
一般描述
23-25kDa
免疫原
Recombinant GRB2/Ash
应用
This Anti-GRB2 Antibody, clone 3F2 is validated for use in IH, WB for the detection of GRB2.
生化/生理作用
N-terminal SH3 region of GRB2
外形
Format: Purified
PBS containing 50% glycerol
分析说明
Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated in immunoblot on RIPA lysates of non-stimulated human A431 carcinoma cells, RIPA lysates of mouse 3T3/A31 fibroblasts, rat L6 myoblasts, Chinese hamster ovary cells or bovine brain extract
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Protein-tyrosine phosphatase 1D modulates its own state of tyrosine phosphorylation
Stein-Gerlach, M., et al
The Journal of Biological Chemistry, 270, 24635-24637 (1995)
M Rozakis-Adcock et al.
Nature, 363(6424), 83-85 (1993-05-06)
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Wang, Y., et al
The Journal of Biological Chemistry, 271, 17-20 (1996)
Ramya Ganesan et al.
Journal of leukocyte biology, 103(5), 867-883 (2018-04-16)
The uptake of cholesterol carried by low-density lipoprotein (LDL) is tightly controlled in the body. Macrophages are not well suited to counteract the cellular consequences of excess cholesterol leading to their transformation into "foam cells," an early step in vascular
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Zhao, H, et al.
The Journal of Biological Chemistry, 272, 21625-21634 (1997)
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