一般描述
56 kDa
免疫原
GST-fusion to residues 1-225 of murine Lck
应用
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
This Anti-Lck Antibody, clone 3A5 is validated for use in IP, WB for the detection of Lck.
生化/生理作用
Recognizes Lck.
外形
Protein A purified
Format: Purified
Protein A purified antibody in 100uL of 10mM PBS, pH 7.4
制备说明
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-372
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.
Jennifer C Paterson, Sara Tedoldi, Andrew Craxton, Margaret Jones, Martin-Leo Hansmann et al.
Haematologica null
Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.
Shuh, M; Morse, BA; Heidecker, G; Derse, D
Journal of virology null
Tiphaine Douanne et al.
Open biology, 14(2), 230456-230456 (2024-02-28)
Cytotoxic T lymphocytes (CTLs) are key effectors of the adaptive immune system that recognize and eliminate virally infected and cancerous cells. In naive CD8+ T cells, T-cell receptor (TCR) engagement drives a number of transcriptional, translational and proliferation changes over
B Omri et al.
Journal of neurochemistry, 67(4), 1360-1364 (1996-10-01)
The lck gene product, p56lck, is a member of the src-related family of protein tyrosine kinases. It is known as lymphocyte specific and involved in thymocyte development and in the immune response mediated by the T cell receptor. We report
Jing Jin et al.
Molecular and cellular biology, 36(6), 1007-1018 (2016-01-13)
The heat shock protein 90 (HSP90) and cell division cycle 37 (CDC37) chaperones are key regulators of protein kinase folding and maturation. Recent evidence suggests that thermodynamic properties of kinases, rather than primary sequences, are recognized by the chaperones. In
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