05-647
Anti-Tyrosinase Antibody, clone T311
clone T311, Upstate®, from mouse
别名:
Anti-Anti-ATN, Anti-Anti-CMM8, Anti-Anti-OCA1, Anti-Anti-OCA1A, Anti-Anti-OCAIA, Anti-Anti-SHEP3
一般描述
70-80kDa
免疫原
Purified recombinant Tyrosinase corresponding to residues 5-456 of human Tyrosinase
应用
Not recommended for Immunoprecipitation
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
Neurofilament & Neuron Metabolism
Neuronal & Glial Markers
This Anti-Tyrosinase Antibody, clone T311 is validated for use in WB, IH for the detection of Tyrosinase.
生化/生理作用
Tyrosinase
外形
Protein G Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
制备说明
2 years at -20°C
分析说明
routinely evaluated by immunoblot on RIPA lysates from SK-MEL-19 cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Structure-toxicity relationship of phenolic analogs as anti-melanoma agents: an enzyme directed prodrug approach.
Vad NM, Kandala PK, Srivastava SK, Moridani MY
Chemico-Biological Interactions null
Hee-Sun Lim et al.
Chonnam medical journal, 52(1), 45-52 (2016-02-13)
As a key regulator of melanogenesis, p53 controls microphthalmia-associated transcription factor (MITF) and tyrosinase expression. The anti-oxidant enzyme heme oxygenase-1 (HO-1) is induced by various forms of cellular stress and diverse oxidative stimuli. However, few studies have examined the role
Y T Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 92(18), 8125-8129 (1995-08-29)
Tyrosinase (EC 1.14.18.1), the key enzyme in melanin synthesis, has been shown to be one of the targets for cytotoxic T-cell recognition in melanoma patients. To develop serological reagents useful for immunophenotyping melanoma for tyrosinase, human tyrosinase cDNA was expressed
Shashi K Kudugunti et al.
Chemico-biological interactions, 188(1), 1-14 (2010-08-06)
In the current work, we investigated the in vitro biochemical mechanism of Caffeic Acid Phenylethyl Ester (CAPE) toxicity and eight hydroxycinnamic/caffeic acid derivatives in vitro, using tyrosinase enzyme as a molecular target in human SK-MEL-28 melanoma cells. Enzymatic reaction models
Nikhil M Vad et al.
International journal of oncology, 35(1), 193-204 (2009-06-11)
Previously, we reported that acetaminophen (APAP) showed selective toxicity towards melanoma cell lines. In the current study, we investigated further the role of tyrosinase in APAP toxicity in SK-MEL-28 melanoma cells in the presence of a short hairpin RNA (shRNA)
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