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Merck
CN

05-736

Anti-phospho-Akt1/PKBα (Ser473) Antibody, clone SK703, rabbit monoclonal

clone SK703, Upstate®, from rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
SK703, monoclonal
Species reactivity:
human, mouse
Application:
WB
Citations:
24
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biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

SK703, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

phosphorylation (pSer473)

Gene Information

human ... AKT1(207)

General description

60kDa

Immunogen

Peptide containing a pSer that corresponds to amino acid position 473 of human Akt1/PKBa

Application

Detect phospho-Akt1/PKBα (Ser473) using this Anti-Akt1 Antibody, clone SK703 validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

Biochem/physiol Actions

phosphorylated Akt1/PKBa

Physical form

Format: Purified
Protein A purified
Protein A purified antibody in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide.

Preparation Note

Stable refrigerated at 2-8°C in undiluted aliquots for up to 1 year from date of receipt.

Analysis Note

routinely evaluated by immunoblot on lysates from mouse NIH-3T3 fibroblasts treated with PDGF

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Matthew J Nelson et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 300(4), R993-R1000 (2011-02-11)
The purpose of this study was to test the hypothesis that exercise-induced cardiac adaptations would be attenuated by the free radical scavenger N-2-mercaptopropionyl glycine (MPG). Male Sprague-Dawley rats were divided into four groups (n = 9-13 per group) for 3-4
Chenran Zhang et al.
BMC cancer, 15, 990-990 (2015-12-23)
Retinoblastoma protein-interacting zinc-finger gene 1 (RIZ1) displays strong tumor suppressive activities, and its expression is often silenced in many types of human tumors. However, the relationship between RIZ1 expression and glioma prognosis remains unclear. The dysregulation of RIZ1 was evaluated
Giorgio Zauli et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 17(4), 762-770 (2010-11-26)
To analyze the effect of the combination of Dasatinib, a multikinase inhibitor, plus Nutlin-3, a nongenotoxic activator of the p53 pathway, in primary B chronic lymphocytic leukemia (B-CLL) patient samples and B leukemic cell line models. The induction of cytotoxicity