Anti-MLL/HRX Antibody, NT., clone N4.4

The acute lymphoblastic leukaemia (ALL)-1 (also known as MLL, HRX, HTRX, and TRX1) gene on human chromosome 11q23 is the site of many locally clustered chromosomal alterations associated with several types of acute leukaemias, including deletions, partial duplications and translocations. Structurally variant proteins derived from the altered gene presumably cause the malignant transformation of early haemopoietic progenitor cells.

300 kDa

MBP fusion protein corresponding to residues 161-356 of human mixed lineage leukemia, MLL

Detect MLL/HRX with Anti-MLL/HRX Antibody, N-term., clone N4.4 (Mouse Monoclonal Antibody), that has been shown to work in IP & WB.

Recognizes N-terminal proteolytic fragment of MLL (MLLN).

Format: Purified

Immunoaffinity Purified immunoglobulin in 0.014M phosphate buffer, pH 7.6, 0.175M NaCl, 0.07% sodium azide, and 30% glycerol.

routinely evaluated by immunoblot on nuclear extract from K562 cells

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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