05-780
Anti-Akt3/PKBγ Antibody, clone GMA104
clone GMA104, Upstate®, from mouse
登录 查看组织和合同定价。
选择尺寸
关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
GMA104, monoclonal
Application:
immunoprecipitation (IP)
western blot
western blot
Species reactivity:
human
Citations:
5
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-Akt3/PKBγ Antibody, clone GMA104, clone GMA104, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
GMA104, monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... AKT3(10000)
Analysis Note
routinely evaluated by immunoblot on RIPA lysates from Jurkat or HL-60 cells
Application
Research Category
Signaling
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
PI3K, Akt, & mTOR Signaling
This Anti-Akt3/PKBγ Antibody, clone GMA104 is validated for use in IP, WB for the detection of Akt3/PKBγ.
Biochem/physiol Actions
Predicted to cross-react with mouse and rat based on sequence homology.
RhoA
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
~60kDa
Immunogen
peptide corresponding to amino acids 119-131 (CSPTSQIDNIGEE) of human Akt3/PKBγ
Physical form
Buffered solution containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Format: Purified
Protein A purified
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
Rebekka Geißert et al.
Cell communication and signaling : CCS, 22(1), 85-85 (2024-01-31)
K-Ras is the most frequently mutated Ras variant in pancreatic, colon and non-small cell lung adenocarcinoma. Activating mutations in K-Ras result in increased amounts of active Ras-GTP and subsequently a hyperactivation of effector proteins and downstream signaling pathways. Here, we
Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
Aroa Soriano et al.
Oncotarget, 7(8), 9271-9287 (2016-01-30)
Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this process is frequently altered
The Akt isoforms are present at distinct subcellular locations.
Santi, SA; Lee, H
American Journal of Physiology. Cell Physiology null
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持