05-857
抗磷酸化-Src家族（Tyr416）抗体，克隆2N8，兔单克隆
clone 2N8, Upstate®, from rabbit
别名:
KAT13A
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
2N8, monoclonal
Species reactivity:
vertebrates, mouse
Application:
WB
Citations:
9
biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
2N8, monoclonal
species reactivity
vertebrates, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pTyr416)
Quality Level
Gene Information
human ... SRC(6714)
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General description
60kDa
Immunogen
含有序列...NE[pY]TA的合成肽，其中pY对应于c-Src 416位的磷酸酪氨酸。
Application
研究子类别
细胞骨架信号转导
细胞骨架信号转导
研究类别
信号传导
信号传导
经验证，该抗磷酸化Src家族（Tyr416）抗体（克隆2N8）可用于WB检测磷酸化Src家族（Tyr416）。
Biochem/physiol Actions
磷酸化-c-Src (Tyr416)
Physical form
形式：纯化
蛋白A纯化
Preparation Note
自运送之日起在-20°C下保存2年
Analysis Note
通过使用抗Src，克隆GD11琼脂糖珠（目录号16-186）免疫印迹从NIH/3T3 RIPA裂解液中免疫沉淀的内源性磷酸化-c-Src进行常规评估
Other Notes
替代：16-249
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
Molecular interdiction of Src-family kinase signaling in hematopoietic cells.
Geahlen, Robert L, et al.
Oncogene, 23, 8024-8032 (2004)
Structure and regulation of Src family kinases.
Boggon, Titus J and Eck, Michael J
Oncogene, 23, 7918-7927 (2004)
The interplay between Src family kinases and receptor tyrosine kinases.
Bromann, Paul A, et al.
Oncogene, 23, 7957-7968 (2004)
Suowen Xu et al.
Cellular signalling, 28(3), 117-124 (2015-12-27)
Endothelial dysfunction, characterized by impaired activation of endothelial nitric oxide (NO) synthase (eNOS) and ensued decrease of NO production, is a common mechanism of various cardiovascular pathologies, including hypertension and atherosclerosis. Laminar blood flow-mediated specific signaling cascades modulate vascular endothelial
Keiji Tamaoki et al.
Cell & bioscience, 6, 2-2 (2016-01-23)
Amphibians are able to survive for several months without food. However, it is unclear what molecular mechanisms underlie their survival. To characterize the intestinal responses to fasting and refeeding, we investigated morphological, biochemical, transcriptional and epigenetic changes in the intestine
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