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05-903

Anti-GSK3α/β Antibody, rabbit monoclonal

Name: Anti-GSK3α/β Antibody, rabbit monoclonal
Brand: MM

Upstate^®, from rabbit

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

monoclonal

Application:

IP, WB

Citations:

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human, mouse

manufacturer/tradename

Upstate^®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

NM_002093, NM_019884

UniProt accession no.

P49840

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GSK3A(2931)

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General description

Mr 46kDa (beta) and 51kDa (alpha)

Immunogen

N-terminal 6His-tagged recombinant full length human GSK3β

Application

Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.

Biochem/physiol Actions

GSK3 alpha and beta

Predicted to cross-react with rat based on sequence homology

Physical form

Format: Purified

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.

routinely evaluated by immunoblot on lysates from HEK293 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1

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Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.

Jope, Richard S

Trends in Pharmacological Sciences, 24, 441-443 (2003)

Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication.

Chuluunbaatar, U; Roller, R; Feldman, ME; Brown, S; Shokat, KM; Mohr, I

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Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse.

Yasuhiro Nishino et al.

Circulation research, 103(3), 307-314 (2008-06-28)

The inactivation of glycogen synthase kinase-3beta (GSK-3beta) is proposed as the event integrating protective pathways initiated by preconditioning and other interventions. The inactivation of GSK-3 is thought to decrease the probability of opening of the mitochondrial permeability transition pore. The

The neuron-specific isoform of glycogen synthase kinase-3beta is required for axon growth.

Casta?o, Zafira, et al.

Journal of Neurochemistry, 113, 117-130 (2010)

GSK-3: tricks of the trade for a multi-tasking kinase.

Doble, Bradley W and Woodgett, James R

Journal of Cell Science, 116, 1175-1186 (2003)

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货号	GTIN
05-903	04053252477843

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