生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
monoclonal
种属反应性
human, mouse
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... GSK3A(2931)
一般描述
Mr 46kDa (beta) and 51kDa (alpha)
免疫原
N-terminal 6His-tagged recombinant full length human GSK3β
应用
Anti-GSK3α/β Antibody is an antibody against GSK3α/β for use in IP & WB.
生化/生理作用
GSK3 alpha and beta
Predicted to cross-react with rat based on sequence homology
外形
Format: Purified
分析说明
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on lysates from HEK293 cells
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
GSK-3: tricks of the trade for a multi-tasking kinase.
Doble, Bradley W and Woodgett, James R
Journal of Cell Science, 116, 1175-1186 (2003)
Jen Q Pan et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 36(7), 1397-1411 (2011-03-11)
Bipolar disorder (BP) is a debilitating psychiatric disorder, affecting ∼2% of the worldwide population, for which the etiological basis, pathogenesis, and neurocircuitry remain poorly understood. Individuals with BP suffer from recurrent episodes of mania and depression, which are commonly treated
Constitutive mTORC1 activation by a herpesvirus Akt surrogate stimulates mRNA translation and viral replication.
Chuluunbaatar, U; Roller, R; Feldman, ME; Brown, S; Shokat, KM; Mohr, I
Genes & Development null
The neuron-specific isoform of glycogen synthase kinase-3beta is required for axon growth.
Casta?o, Zafira, et al.
Journal of Neurochemistry, 113, 117-130 (2010)
Lithium and GSK-3: one inhibitor, two inhibitory actions, multiple outcomes.
Jope, Richard S
Trends in Pharmacological Sciences, 24, 441-443 (2003)
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