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Merck
CN

05-940

Anti-INCENP Antibody, clone 58-217

clone 58-217, Upstate®, from mouse

别名:

Anti-2700067E22Rik, Anti-C130081E20, Anti-C77457

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
58-217, monoclonal
Application:
western blot
Species reactivity:
human
Citations:
10
Technique(s):
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-INCENP Antibody, clone 58-217, clone 58-217, Upstate®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

58-217, monoclonal

species reactivity

human

should not react with

rat, mouse

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... INCENP(3619)

Analysis Note

Routinely evaluated by immunoblot.

Application

Detect INCENP with Anti-INCENP Antibody, clone 58-217 (Mouse Monoclonal Antibody), that has been shown to work in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

INCENP

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

135-155kDa

Immunogen

6His tagged fusion protein corresponding to residues 231-398 of human Inner Centromere Protein (INCENP). Clone 58-217.

Physical form

Format: Purified
Protein G Purified

Preparation Note

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 1


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Sally P Wheatley et al.
The Journal of biological chemistry, 279(7), 5655-5660 (2003-11-12)
The chromosomal passengers, aurora-B kinase, inner centromere protein (INCENP), and survivin, are essential proteins that have been implicated in the regulation of metaphase chromosome alignment, spindle checkpoint function, and cytokinesis. All three share a common pattern of localization, and it
Interphase cytofission maintains genomic integrity of human cells after failed cytokinesis.
Choudhary, A; Lera, RF; Martowicz, ML; Oxendine, K; Laffin, JJ; Weaver, BA; Burkard, ME
Proceedings of the National Academy of Sciences of the USA null
Ulrike Gruneberg et al.
The Journal of cell biology, 166(2), 167-172 (2004-07-21)
Mitotic kinases of the Polo and Aurora families are key regulators of chromosome segregation and cytokinesis. Here, we have investigated the role of MKlp1 and MKlp2, two vertebrate mitotic kinesins essential for cytokinesis, in the spatial regulation of the Aurora
Reiko Honda et al.
Molecular biology of the cell, 14(8), 3325-3341 (2003-08-20)
The function of the Aurora B kinase at centromeres and the central spindle is crucial for chromosome segregation and cytokinesis, respectively. Herein, we have investigated the regulation of human Aurora B by its complex partners inner centromere protein (INCENP) and
Asha Recino et al.
The Biochemical journal, 430(2), 207-213 (2010-07-16)
RASSF7, a member of the N-terminal Ras association domain family, has increased expression in various cancers and, on the basis of our previous work in Xenopus embryos, may be a regulator of mitosis. In the present study, we address, for

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