biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
3-11, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgM
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRO(7216)
General description
69 kDa
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 1319-1327 (SIVGFSGGP-C) of human Trophinin (MAGE-D3)
Application
Anti-Trophinin Antibody, clone 3-11 detects level of Trophinin & has been published & validated for use in IP, WB, IH.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Biochem/physiol Actions
Trophinin (MAGE-D3)
Physical form
Cell culture supernatant containing 0.05% sodium azide and 30% glycerol
Preparation Note
2 years at -20°C from date of shipment
Analysis Note
Routinely evaluated by immunoblot in RIPA lysates from HT-H cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
The MAGE proteins: emerging roles in cell cycle progression, apoptosis, and neurogenetic disease.
Barker, Philip A and Salehi, Amir
Journal of Neuroscience Research, 67, 705-712 (2002)
R Aoki et al.
Seminars in reproductive medicine, 18(3), 265-271 (2001-04-13)
Elucidation of the implantation mechanism in humans at the molecular level has been difficult because of methodological restrictions. Instead of using human materials during the implantation period, two human tumor cell lines that respectively mimic the biological behaviors of a
Cancer/testis antigens: structural and immunobiological properties.
Kirkin, Alexei F, et al.
Cancer Investigation, 20, 222-236 (2002)
Kazuhiro Sugihara et al.
FEBS letters, 582(2), 197-202 (2007-12-15)
During embryo implantation, trophinin mediates cell adhesion by homophilic binding at the apical surfaces of trophectoderm and endometrium. Trophinin is expressed on the human endometrial epithelia in rare occasions. We developed hCG-coated agarose beads that mimic the physical and physiological
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