biological source
mouse
conjugate
unconjugated
antibody form
culture supernatant
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TCL1A(8115)
General description
14 kD
Immunogen
KLH-conjugated, synthetic peptide corresponding to amino acids 60-73 (RPMTPTQIGPSLLP) of human TCL1A
Application
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
This Anti-TCL1 Antibody is validated for use in WB, IH for the detection of TCL1.
Biochem/physiol Actions
TCL1A, no cross-reactivity with TML1 (TCL1B) or MTCP1
Physical form
Cell culture supernatant
Preparation Note
2 years at -20°C from date of shipment
Analysis Note
Routinely evaluated by immunoblot in RIPA lysates from Raji cells
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
A systematic approach to diagnosis of mature T-cell leukemias reveals heterogeneity among WHO categories
Herling, M. et al.
Blood, 104, 328-335 (2004)
TCL1: a new drug target in lymphoid and germ-cell malignancies?
Lock, Richard B
The International Journal of Biochemistry & Cell Biology, 35, 1614-1618 (2003)
TCL1 is a diagnostic marker for intratubular germ cell neoplasia and classic seminoma.
Dengfeng Cao,Zhaoli Lane,Robert William Allan,Peng Wang,Charles Chuanhai Guo,Yan Peng,Jianping Li
Histopathology null
Structural basis for the co-activation of protein kinase B by T-cell leukemia-1 (TCL1) family proto-oncoproteins.
Auguin, Daniel, et al.
The Journal of Biological Chemistry, 279, 35890-35902 (2004)
Crystal structures of Tcl1 family oncoproteins and their conserved surface features.
Petock, John M, et al.
TheScientificWorldJournal, 2, 1876-1884 (2002)
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