06-1367
Anti-SRp75 Antibody
from rabbit
别名:
serine/arginine-rich splicing factor 4, splicing factor, arginine/serine-rich 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human, mouse, rat
Citations:
2
Technique(s):
western blot: suitable
Uniprot accession no.:
产品名称
Anti-SRp75 Antibody, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse, rat
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SRSF4(6429)
Analysis Note
Evaluated by Western Blot in L6 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.
Western Blot Analysis: 1:500 dilution of this antibody detected SRp75 on 10 µg of L6 cell lysate.
Application
Anti-SRp75 Antibody is a rabbit polyclonal antibody for detection of SRp75 also known as serine/arginine-rich splicing factor 4, SR splicing factor 4, Pre-mRNA-splicing factor SRP75 & has been validated in WB.
Immunoprecipitation Analysis: A reprentative lot of this antibody was used by an independent laboratory in IP. (Jiang, K., et al. (2009). Endocrinology. 150(5):2087-2097.)
General description
SRp75, also known as Serine/arginine-rich splicing factor 4, is an essential splicing factor that is a member of the SR family of proteins. This protein is a component of the pre-mRNA splicing complex and is believed to play a role in alternative splice site selection. Consistent with this excess levels of SRp75 have been shown to play a role in alternative splicing of CD45. SRp75 is normally found in the nucleus and is known to be hyperphosphorylated at serine residues in its RS domain.
~ 62 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human SRp75.
Physical form
Format: Purified
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Paul L Boutz et al.
Genes & development, 29(1), 63-80 (2015-01-07)
Deep sequencing of embryonic stem cell RNA revealed many specific internal introns that are significantly more abundant than the other introns within polyadenylated transcripts; we classified these as "detained" introns (DIs). We identified thousands of DIs, many of which are
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins.
Hinkle, et al.
Communications biology, 5, 987-987 (2022)
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