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Merck
CN

06-1376

Anti-SLBP Antibody

serum, from rabbit

别名:

Histone stem-loop-binding protein, hairpin binding protein, histone binding protein 2, histone stem-loop binding protein, stem-loop (histone) binding protein, stem-loop binding protein, HBP, Histone RNA hairpin-binding protein

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ICC, WB
Citations:
-
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biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

species reactivity (predicted by homology)

rat

technique(s)

immunocytochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SLBP(7884)

General description

38 kDa
The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.

Application

Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.
Research Sub Category
RNA Metabolism & Binding Proteins

Histones
Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.

Biochem/physiol Actions

Antibody recognizes SLBP.

Physical form

Serum in buffer containing 0.05% sodium azide

Analysis Note

Control
C2C12 cell lysates.
Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.

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存储类别

10 - Combustible liquids

wgk

WGK 1


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