产品名称
Giα1/2抗体, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat, bovine
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GNAI1(2770)
Analysis Note
通过免疫印迹法对大鼠脑微粒体制备物或小鼠3T3/A31成纤维细胞的溶解质膜进行了常规评估
对照
广泛表达
广泛表达
Application
可使用这种经验证可用于IC、IP & WB的Giα1/2抗体检测Giα1/2。
研究子类别
GPCR, cAMP/cGMP & 钙信号传导
GPCR, cAMP/cGMP & 钙信号传导
研究类别
信号传导
信号传导
Biochem/physiol Actions
可识别Giα1和Giα2。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
40 kDa
Immunogen
10个残基的合成肽（KNNLKDCGLF），对应于Gia1和Gia2的C端
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
PBS（50 mM KHPO4、140 mM NaCl）稀释的兔血清。冷冻溶液
形式：纯化
Preparation Note
自收到之日起在-20°C可稳定保存2年。避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始小瓶进行离心。
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
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During antidiuresis, increases in vasopressin (AVP)-elicited osmotic water permeability in the terminal inner medullary collecting duct (tIMCD) raise luminal calcium concentrations to levels (> or = 5 mM) above those associated with the formation of calcium-containing precipitates in the urine.
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Mimicking short photoperiod melatonin signals (16 h exposure) on primary cell cultures of melatonin target cells of the ovine pars tuberalis (PT) results in an enhanced cAMP response to forskolin stimulation relative to untreated cells, a phenomenon termed sensitization. The
Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro
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The Journal of Biological Chemistry, 273, 14476-14483 (1998)
Jian Shi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(2), 702-715 (2015-10-16)
Depletion of sarcoplasmic reticulum (SR) Ca(2+) stores activates store-operated channels (SOCs) composed of canonical transient receptor potential (TRPC) 1 proteins in vascular smooth muscle cells (VSMCs), which contribute to important cellular functions. We have previously shown that PKC is obligatory
Alejandro Balbis et al.
Endocrinology, 148(6), 2944-2954 (2007-03-17)
In this study, the preparation of detergent-resistant membranes (DRMs) and the immunoisolation of intracellular vesicles enriched in raft markers were used to investigate the effect of physiological doses of epidermal growth factor (EGF) in vivo on the compartmentalization and activation
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