生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rabbit, hamster, mouse, human, rat
制造商/商品名称
Upstate®
技术
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... JAK1(3716)
一般描述
130 kDa
免疫原
HPLC-purified (>98%) peptide corresponding to 21 amino acids of human JAK1 (KTLIEKERFYESRCRPVTPS-C)
应用
Anti-JAK1 Antibody detects level of JAK1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
生化/生理作用
JAK1
外形
Antiserum
whole rabbit antiserum containing 0.05% sodium azide
制备说明
2 years at -20°C
分析说明
routinely evaluated by immunoblot on RIPA lysate from mouse CTLL lymphocytes, TF-1 erythroleukemic cells or mouse thymus
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.
Tortolani, P J, et al.
Blood, 85, 3444-3451 (1995)
Intermediate affinity interleukin-2 receptor mediates survival via a phosphatidylinositol 3-kinase-dependent pathway
Gonzalez-Garcia, A., et al
The Journal of Biological Chemistry, 272, 10220-10226 (1997)
C F Lai et al.
The Journal of biological chemistry, 274(12), 7793-7802 (1999-03-13)
Interleukin (IL)-6 is a major regulator of hepatic acute-phase plasma protein (APP) genes. The membrane-proximal 133-amino acid cytoplasmic domain of glycoprotein (gp) 130, containing one copy of the Box3 motif, is sufficient to transmit a productive signal to endogenous APP
Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation
Yu, C. L. and Burakoff, S. J.
The Journal of Biological Chemistry, 272, 14017-14020 (1997)
G J Brunn et al.
The Journal of biological chemistry, 270(19), 11628-11635 (1995-05-12)
The proliferation of activated T lymphocytes is critically dependent on the binding of the T-cell growth factors, interleukin (IL)-2 and IL-4, to distinct but evolutionarily related cell surface receptors. Previous results suggest that the IL-2 receptor (IL-2R) and IL-4R are
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