biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... STAT5B(6777)
General description
90-92kDa
Immunogen
amino acids 774-787 of human STAT5B (CGRPMDSQWIPHAQS)
Application
Anti-STAT5B Antibody is a Rabbit Polyclonal Antibody for detection of STAT5B also known as signal transducer & activator of transcription 5B & has been tested in WB.
Physical form
Format: Purified
Analysis Note
Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on mouse 3T3/A31 or human A431 cell lysates
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
J X Lin et al.
The Journal of biological chemistry, 271(18), 10738-10744 (1996-05-03)
We have isolated a second human Stat5 cDNA, Stat5B, and demonstrated that the genes encoding both Stat5A and Stat5B are located at chromosome 17q11.2. Both genes were constitutively transcribed in peripheral blood lymphocytes. By using specific antisera, we demonstrated that
Benjamin Millot et al.
The Biochemical journal, 372(Pt 1), 41-52 (2003-02-13)
The upstream regulatory regions of the mouse and rabbit whey acidic protein (WAP) genes have been used extensively to target the efficient expression of foreign genes into the mammary gland of transgenic animals. Therefore both regions have been studied to
Src Kinases Mediate STAT Growth Pathways in Squamous Cell Carcinoma of the Head and Neck
Xi, S., et al
The Journal of Biological Chemistry, 278, 31574-31583 (2003)
B Millot et al.
The Biochemical journal, 359(Pt 3), 557-565 (2001-10-24)
The aim of the present study was to identify the functional domains of the upstream region of the rabbit whey acidic protein (WAP) gene, which has been used with considerable efficacy to target the expression of several foreign genes to
Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.
Ghosh, P; Buchholz, MA; Yano, S; Taub, D; Longo, DL
Blood null
相关内容
The Janus kinase (JAK)/signal transducers and activators of transcription (STAT) signaling pathway plays an important role in cell proliferation, cell differentiation, cell migration, and cell death. It is the principal signaling mechanism for a variety of cytokines and growth factors. Constitutive activation or dysregulation of JAK/STAT signaling can result in inflammatory disease, erythrocytosis, gigantism, and leukemia.
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