产品名称
抗钙网蛋白抗体, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
pig, human, mouse, Xenopus, bovine, rat
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CALR(811)
Analysis Note
对照
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
已通过免疫印迹法对鼠3T3/NIH成纤维细胞的RIPA裂解液进行了常规评估
Application
抗钙网蛋白抗体是针对钙网蛋白的抗体，用于 IC、IH& WB。
研究子类别
PI3K、Akt & mTOR信号传导
酶&生物化学
PI3K、Akt & mTOR信号传导
酶&生物化学
Biochem/physiol Actions
钙网蛋白；不与其它内质网蛋白反应。
General description
60kDa
Immunogen
对应于人钙网蛋白C末端（氨基酸412-417）的肽（QAKDEL）。
Other Notes
替代：MABT145
Physical form
0.1M Tris-甘氨酸（pH 7.0），0.15M NaCl与0.05％叠氮化钠。
形式：纯化
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Maria L Valencik et al.
Circulation research, 99(12), 1403-1410 (2006-11-11)
Integrins mechanically link the cytoskeleton to the extracellular matrix in cardiac myocytes and are thereby involved in mechanotransduction. Integrins appear to be necessary for cardiac myocyte hypertrophy. To determine the effect of increased integrin ligation and signaling on adult cardiac
M Waser et al.
The Journal of cell biology, 138(3), 547-557 (1997-08-11)
We have isolated and characterized a 12-kb mouse genomic DNA fragment containing the entire calreticulin gene and 2.14 kb of the promoter region. The mouse calreticulin gene consists of nine exons and eight introns, and it spans 4.2 kb of
Takashi Tajima et al.
Proteomes, 7(2) (2019-04-13)
Myxoid liposarcoma (MLS) is a mesenchymal malignancy. To identify innovate seeds for clinical applications, we examined the proteomes of primary tumor tissues from 10 patients with MLS with different statuses of postoperative metastasis. The protein expression profiles of tumor tissues
Calreticulin.
K H Krause et al.
Cell, 88(4), 439-443 (1997-02-21)
Mohan Nair et al.
International journal of molecular sciences, 19(2) (2018-02-15)
Dispersal of Glioblastoma (GBM) renders localized therapy ineffective and is a major cause of recurrence. Previous studies have demonstrated that Dexamethasone (Dex), a drug currently used to treat brain tumor-related edema, can also significantly reduce dispersal of human primary GBM
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