biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
pig, human, mouse, Xenopus, bovine, rat
manufacturer/tradename
Upstate®
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... CALR(811)
General description
60kDa
Immunogen
对应于人钙网蛋白C末端（氨基酸412-417）的肽（QAKDEL）。
Application
抗钙网蛋白抗体是针对钙网蛋白的抗体，用于 IC、IH& WB。
研究子类别
PI3K、Akt & mTOR信号传导
酶&生物化学
PI3K、Akt & mTOR信号传导
酶&生物化学
Biochem/physiol Actions
钙网蛋白；不与其它内质网蛋白反应。
Physical form
0.1M Tris-甘氨酸（pH 7.0），0.15M NaCl与0.05％叠氮化钠。
形式：纯化
Analysis Note
对照
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
阳性抗原对照：货号12-305，3T3/A31裂解液。添加2.5 μL 2-巯基乙醇/100 μL裂解液，煮沸5分钟以还原 制剂。在微凝胶每个泳道上样20 μg经还原的裂解液。
已通过免疫印迹法对鼠3T3/NIH成纤维细胞的RIPA裂解液进行了常规评估
Other Notes
替代：MABT145
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Calreticulin inhibits glucocorticoid- but not cAMP-sensitive expression of tyrosine aminotransferase gene in cultured McA-RH7777 hepatocytes.
Burns, K, et al.
Molecular and Cellular Biochemistry, 171, 37-43 (1997)
Endoplasmic reticulum form of calreticulin modulates glucocorticoid-sensitive gene expression.
Michalak, M, et al.
The Journal of Biological Chemistry, 271, 29436-29445 (1996)
Maria L Valencik et al.
Circulation research, 99(12), 1403-1410 (2006-11-11)
Integrins mechanically link the cytoskeleton to the extracellular matrix in cardiac myocytes and are thereby involved in mechanotransduction. Integrins appear to be necessary for cardiac myocyte hypertrophy. To determine the effect of increased integrin ligation and signaling on adult cardiac