06-709
Anti-Gq/11α Antibody, CT
Upstate®, from rabbit
别名:
Anti-FBH, Anti-FHH2, Anti-GNA-11, Anti-HG1K, Anti-HHC2, Anti-HYPOC2
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
30
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... GNA11(2767)
mouse ... Gna11(14672)
General description
42kDa
Immunogen
peptide (QLNLKEYNLV) corresponding to amino acids 350-359 of Gqα or G11α
Application
Research Category
Signaling
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling
GPCR, cAMP/cGMP & Calcium Signaling
This Anti-Gq/11α Antibody, CT is validated for use in IP, WB for the detection of Gq/11α.
Biochem/physiol Actions
Gqα and G11α
Physical form
Format: Purified
PBS, pH 7.4
Protein A chromatography
Preparation Note
2 years at -20°C
Analysis Note
routinely evaluated by immunoblot on rat brain microsomal preparation
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Justyna Róg et al.
Biochimica et biophysica acta. Molecular basis of disease, 1865(6), 1138-1151 (2019-01-27)
Pathophysiology of Duchenne Muscular Dystrophy (DMD) is still elusive. Although progressive wasting of muscle fibres is a cause of muscle deterioration, there is a growing body of evidence that the triggering effects of DMD mutation are present at the earlier
Margarida Ressurreição et al.
Scientific reports, 6, 35614-35614 (2016-10-21)
During infection of their human definitive host, schistosomes transform rapidly from free-swimming infective cercariae in freshwater to endoparasitic schistosomules. The 'somules' next migrate within the skin to access the vasculature and are surrounded by host molecules that might activate intracellular
4-Hydroxynonenal, an aldehydic product of lipid peroxidation, impairs signal transduction associated with muscarinic acetylcholine and metabotropic glutamate receptors: possible action on G alpha(q/11).
Blanc, E M, et al.
Journal of Neurochemistry, 69, 570-580 (1997)
Jérôme Lannes et al.
Scientific reports, 6, 31563-31563 (2016-08-20)
The GnRH neurohormone is the main activator of the pituitary gonadotropins, LH and FSH. Here we investigated the contribution of microRNAs in mediating GnRH activation. We first established that miR-125b targets several actors of Gαq/11 signalling pathway, without altering Gαs
B Kühn et al.
Molecular endocrinology (Baltimore, Md.), 10(12), 1697-1707 (1996-12-01)
In several cell systems histamine has been shown to stimulate both adenylyl cyclase and phospholipase C through activation of a G protein-coupled H2 receptor. To analyze the bifurcating signal emanating from the activated H2 receptor and to identify the G
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