Anti-Frizzled 5 Antibody

Frizzled 5 (62kDa)

The Wnt family consists of ligands involved in cell fate determination, organogenesis, and oncogenesis. The Wnt signal is thought to be transduced sequentially via a homolog of the frizzled family of receptors to GSK-3 (disheveled), β- and γ- catenin and finally to members of the Tcf/Lef-1 family of HMG box transcription factors. Frizzled 5 is believed to function as the receptor for the Wnt5a ligand.

Epitope: C-Terminus

KLH-conjugated, synthetic peptide derived from amino acids 564-585 of human Frizzled 5 (CTGRTPPGPAATYHKQVSLSHV).

Anti-Frizzled 5 Antibody is an antibody against Frizzled 5 for use in WB.

Research Category
Signaling

Research Sub Category
Developmental Signaling

GPCR, cAMP/cGMP & Calcium Signaling

Frizzled 5 (aka Fz5 or Fzd5)

Format: Purified

Protein A chromatography

Purified antibody in PBS with 0.05% sodium azide and 30% Glycerol

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Control
Lysates from mouse liver, C2C12, Jurkat, and HUVEC

Routinely evaluated by immunoblot on lysates from mouse liver, C2C12, Jurkat or HUVEC cells

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