biological source
rabbit
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, canine, human, mouse
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Quality Level
Gene Information
human ... ADD3(120)
General description
80kDa、120kDa、110kDa
Immunogen
对应于人γ内收蛋白氨基酸656-668的肽(C-KKFRTPpSFLKKNK)
Application
研究子类别
细胞骨架
细胞骨架
研究类别
细胞结构
细胞结构
该抗磷酸化内收蛋白(Ser662)抗体经验证可用于WB中磷酸化内收蛋白(Ser662)的检测。
Biochem/physiol Actions
γ-内收蛋白的磷酸化丝氨酸662、α-内收蛋白的磷酸化丝氨酸724、β-内收蛋白的磷酸化丝氨酸713
Physical form
0.014 M磷酸盐缓冲液(pH 7.6)、0.175 M NaCl、0.07%叠氮化钠和30%甘油。 在-20°C为液体形式。
免疫亲和纯化
Preparation Note
在-20°C下保存1年
Analysis Note
已通过免疫印迹对3T3/NIH细胞或犬MDCK细胞的RIPA裂解液进行了常规评估
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
Transformation-sensitive changes in expression, localization, and phosphorylation of adducins in renal proximal tubule epithelial cells.
Fowler, L, et al.
Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research, 9, 177-184 (1998)
Andrew M Hau et al.
The American journal of pathology, 189(9), 1846-1862 (2019-06-15)
The mammalian target of rapamycin (mTOR) and associated phosphatidylinositol 3-kinase/AKT/mTOR signaling pathway is commonly up-regulated in cancer, including bladder cancer. mTOR complex 2 (mTORC2) is a major regulator of bladder cancer cell migration and invasion, but the mechanisms by which
L Dong et al.
The Journal of biological chemistry, 270(43), 25534-25540 (1995-10-27)
We recently cloned a partial cDNA (35H) for a protein kinase C (PKC) binding protein from a rat kidney cDNA library and demonstrated that it is a PKC substrate in vitro (Chapline, C., Ramsay, K., Klauck, T., and Jaken, S.
Cocaine and habit training cause dendritic spine rearrangement in the prelimbic cortex.
Sequeira, et al.
iScience, 26, 106240-106240 (2023)
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