产品名称
Anti-FLIP Antibody, CT, Upstate®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CFLAR(8837)
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on Jurkat, A431, Raji, 3T3, CTLL, PC12 or L6 RIPA cell lysates
Application
Detect FLIP using this Anti-FLIP Antibody, CT validated for use in WB.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Biochem/physiol Actions
long form of FLIP
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
55kDa
Immunogen
peptide corresponding to amino acids 447-464 [NGYMYDWNSRVSAKEKYY] of human FLIP
Physical form
Format: Purified
PBS, pH 7.4, 0.02% sodium azide before the addition of glycerol to 30%
Protein A chromatography
Preparation Note
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Phosphatidylinositol 3-kinase/Akt signaling mediates interleukin-6 protection against p53-induced apoptosis in M1 myeloid leukemic cells.
Vesely, DL; Hoffman, B; Liebermann, DA
Oncogene null
Predisposition to apoptosis in keratin 8-null liver is related to inactivation of NF-?B and SAPKs but not decreased c-Flip.
Lee, J; Jang, KH; Kim, H; Lim, Y; Kim, S; Yoon, HN; Chung, IK; Roth, J; Ku, NO
Biology Open null
Paola De Cicco et al.
Frontiers in pharmacology, 8, 65-65 (2017-03-16)
Melanoma is the most common form of skin cancer. Given its high mortality, the interest in the search of preventive measures, such as dietary factors, is growing significantly. In this study we tested, in vitro and in vivo, the potential
Elisabetta Panza et al.
Pigment cell & melanoma research, 28(1), 61-72 (2014-09-11)
In humans, two main metabolic enzymes synthesize hydrogen sulfide (H2 S): cystathionine γ lyase (CSE) and cystathionine β synthase (CBS). A third enzyme, 3-mercaptopyruvate sulfurtransferase (3-MST), synthesizes H2 S in the presence of the substrate 3-mercaptopyruvate (3-MP). The immunohistochemistry analysis
F-box protein 10, an NF-?B-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway.
Ge, R; Wang, Z; Zeng, Q; Xu, X; Olumi, AF
Cell Death and Differentiation null
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