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Merck
CN

07-1521

Anti-phospho-NDRG3 (Ser331) Antibody

from rabbit, purified by affinity chromatography

别名:

Protein NDRG3, Protein Ndr3

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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产品名称

Anti-phospho-NDRG3 (Ser331) Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

horse, mouse

species reactivity (predicted by homology)

bovine (based on 100% sequence homology), equine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), rat (based on 100% sequence homology), human (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_038893

UniProt accession no.

Q9QYF9

shipped in

wet ice

target post-translational modification

phosphorylation (pSer331)

Gene Information

bovine ... Ndrg3(514399)
chimpanzee ... Ndrg3(735544)
human ... NDRG3(57446)
mouse ... Ndrg3(29812)
rat ... Ndrg3(296318)

Analysis Note

Control
Mouse embryonic fibroblast cell lysates under multiple conditions (see image).
Evaluated by Western Blot in mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Western Blot Analysis: 0.1 µg/mL of this antibody detected NDRG3 on 10 µg of mouse embryonic fibroblast cell lysates under multiple conditions (see image).

Application

Detect phospho-NDRG3 (Ser331) using this Anti-phospho-NDRG3 (Ser331) Antibody validated for use in Western Blotting.
Research Category
Signaling
Research Sub Category
Developmental Signaling

Biochem/physiol Actions

This antibody recognizes NDRG3 phosphorylated at (Ser331).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

NDGR3 is a member of the N-myc down-regulated gene (NDGR) family which includes NDGR1-4. NDGR3 is ubiquitously expressed but is abundant in the brain, testis, prostate, and ovary. The precise role of NDGR3 has not been elucidated; however, previous studies have suggested that NDGR3 may play a role in spermatogenesis in mice, and aberrant expression of NDGR3 may lead to the proliferation of prostate cancer cells. NDGR3-mediated tumor growth may be due to upregulation of various angiogenic chemokines such as chemokine ligands 1, 3, and 5, which promote angiogenesis in tumors.
~33 kDa observed

Immunogen

Epitope: Phosphorylated (Ser331)
KLH-conjugated linear peptide corresponding to mouse NDRG3 phosphorylated at (Ser331).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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